Results 101 to 110 of about 47,605 (207)
Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He +7 more
wiley +1 more source
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu +5 more
wiley +1 more source
Heteroresistance to carbapenems in Acinetobacter baumannii [PDF]
S, Pournaras +4 more
openaire +2 more sources
Objectives: Acinetobacter baumannii is an omnipresent pathogen known as a major agent in healthcare and nosocomoal-associated infections. Its ability to develop resistant pattern to the major and broad spectrum antibiotics is an important issue to be ...
Parviz Vahdani +2 more
doaj
Wastewater from urban and rural areas was analyzed to investigate antimicrobial‐resistant bacteria and resistance genes. ESBL‐Escherichia coli and genes coding for clinically relevant resistances, namely, those to macrolides, carbapenems, and vancomycin, were higher in urban than in rural areas.
Maya Petricciuolo +7 more
wiley +1 more source
Multivalent Glycopolymer Design Unlocks Antimicrobial Activity of 2‐Deoxyglucose
New approaches to combat antimicrobial‐resistant pathogens are needed. Here, scaffolding a nonmetabolizable sugar (2DG) on a polymer backbone is shown to significantly improve its antimicrobial activity. ABSTRACT With the increasing prevalence of multidrug‐resistant (MDR) pathogens, last‐line therapeutics such as cyclic peptides are insufficient ...
Sungjin Jeon +4 more
wiley +2 more sources
Prognostic Factors That Affect Mortality Patients with Acinetobacter baumannii Bloodstream Infection
Chunrong Huang,1,2,* Yulian Gao,1,2,* Hongxia Lin,1– 3,* Qinmei Fan,4,* Ling Chen,1,2 Yun Feng1,2 1Department of Respiratory and Critical Care Medicine, Ruijin Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai,
Huang C +5 more
doaj
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang +8 more
wiley +1 more source
The World Health Organization (WHO) cites antimicrobial resistance as among the greatest threats to human health. The multidrug-resistant pathogen Acinetobacter baumannii, recognized as a priority pathogen for healthcare and research, is responsible for ...
Kailey Martz +4 more
doaj +1 more source

