Results 71 to 80 of about 100,585 (295)
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo+2 more
wiley +1 more source
Extended-Spectrum Cephalosporinase in Acinetobacter baumannii [PDF]
ABSTRACT An AmpC-type β-lactamase conferring high-level resistance to expanded-spectrum cephalosporins and monobactams was characterized from an Acinetobacter baumannii clinical isolate. This class C β-lactamase (named ADC-33) possessed a Pro210Arg substitution together with a duplication of an Ala residue
José-Manuel Rodríguez-Martínez+3 more
openaire +3 more sources
Multidrug-resistant Acinetobacter baumannii clones persist on hospital inanimate surfaces
Acinetobacter baumannii is one of the most frequent Gram-negative opportunistic pathogens associated with hospital-acquired infection worldwide. We briefly describe A.
Igor Vasconcelos Rocha+4 more
doaj +1 more source
Background: The management of Acinetobacter baumannii infection is considered a challenge especially in an intensive care setting. The resistance rate makes it difficult to manage and is believed to lead to higher mortality.
Thabit Alotaibi+5 more
doaj +1 more source
Synthesis and evaluation of troponoids as a new class of antibiotics [PDF]
Novel antibiotics are urgently needed. The troponoids [tropones, tropolones, and α-hydroxytropolones (α-HT)] can have anti-bacterial activity. We synthesized or purchased 92 troponoids and evaluated their antibacterial activities against Staphylococcus ...
Adegboyega, Patrick+8 more
core +4 more sources
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou+4 more
wiley +1 more source
Kemampuan hidup Acinetobacter baumannii pada berbagai keadaan dikombinasikan dengan resistensi berkaitan erat dengan Healthcare Associated Infections (HAIs). Kemunculan strain resisten telah banyak dilaporkan.
Wilda Mahdani+2 more
doaj +1 more source
Evaluation of the Blue-Carba test for rapid detection of carbapenemases in gram-negative Bacilli [PDF]
The Blue-Carba test (BCT) is a biochemical test for rapid (2 h)detection of carbapenemase production in Gram-negative bacillidirectly from bacterial culture .
Albornoz, Ezequiel Pablo+7 more
core +1 more source
The lipoprotein transport system (Lol) is a crucial target for combating multidrug‐resistant gram‐negative bacteria. This review discusses the structural and functional aspects of the LolABCDE complex, recent advances in small‐molecule inhibitors, and challenges, such as permeability and resistance.
Saemee Song, Su Yong Shim
wiley +1 more source
Genomics of Acinetobacter baumannii iron uptake
Iron is essential for growth in most bacteria due to its redox activity and its role in essential metabolic reactions; it is a cofactor for many bacterial enzymes. The bacterium Acinetobacter baumannii is a multidrug-resistant nosocomial pathogen.
Irene Artuso+3 more
openaire +4 more sources