Results 101 to 110 of about 5,038 (172)

Divergent gene signatures and neutrophil enrichment in lymph nodes of inflammatory arthritis patients

Arthritis Research & Therapy
Background Lymph node (LN) studies in anti-cyclic citrullinated protein antibodies (ACPA) positive rheumatoid arthritis (RA) patients have revealed notable alterations in adaptive immune cell populations.
Aoife M. O’Byrne, Janne W. Bolt, Chaja M.J. van Ansenwoude, Martijn van der Heijde, Johanna F. Semmelink, Aldo Jongejan, Perry D. Moerland, Mario Maas, Marleen G.H. van de Sande, Lisa G.M. van Baarsen   +9 more
doaj   +1 more source

Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Do Not Arrest Bone Loss in Patients With Rheumatoid Arthritis: A Long‐Term Multicenter Observational Study

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2036-2049, October 2026.
Objective Osteoporosis causes fractures that further increase the disease burden of rheumatoid arthritis (RA); however, osteoporosis treatment rates remain low. Although several studies have reported that biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) can prevent or improve osteoporosis in RA, our large‐scale, real ...
Takafumi Aritomi, Koshiro Sonomoto, Shingo Nakayamada, Hiroaki Tanaka, Atsushi Nagayasu, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Naoaki Ohkubo, Yasuyuki Todoroki, Yurie Satoh‐Kanda, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Masashi Funada, Hidenori Sakai, Satsuki Matsunaga, Hiroaki Tanaka, Masayuki Shinojima, Hiroki Kawamura, Kazuki Takahashi, Miyabi Ando, Kazuki Haru, Yusuke Miyazaki, Kentaro Hanami, Masao Nawata, Shunsuke Fukuyo, Keisuke Nakatsuka, Mikiko Tokunaga, Kazuyoshi Saito, Yoshiya Tanaka   +30 more
wiley   +1 more source

Olaparib‐associated cutaneous vasculitis in a patient with breast cancer

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Marcial Álvarez‐Salafranca, Teresa Puértolas, Adrián Diago, María Carmen Gómez‐Mateo   +3 more
wiley   +1 more source

Response to the ACPA's Critique [PDF]

Environmental Health Perspectives, 1998
R Repetto, S Baliga
openaire   +1 more source

Special issue on 4th ACPA [PDF]

Precision Agriculture, 2013
I would like to express my appreciation to the 18 paper authors and more than 40 reviewers, as well as Dr. J. Stafford as the editor-in-chief and Dr. J. Schepers as the coeditor-in-chief, for their great efforts. After the peer review, three papers were accepted.
openaire   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2149-2159, October 2026.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2074-2081, October 2026.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

Discovery of Post‐Translationally Modified Epitopes in Autoimmunity: Someone Has to Fish so Everyone Can Eat

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Post‐translational modifications (PTMs) chemically diversify the ~20,000 genomically encoded proteins into millions of functional variants, and this diversity has profound consequences for T cell‐mediated immune responses. PTM‐reactive T cells have been identified across numerous autoimmune diseases and, in several cases, implicated directly ...
Sanya Arshad, Benjamin M. Cameron, Alok V. Joglekar   +2 more
wiley   +1 more source

Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: A meta-analysis of genome-wide association study in a Japanese population [PDF]

, 2015
Introduction: Although susceptibility genes for anti-citrullinated peptide/protein antibodies (ACPA)-positive rheumatoid arthritis (RA) have been successfully discovered by genome-wide association studies (GWAS), little is known about the genetic ...
Takeuchi, Tsutomu, Akari Suzuki, Kochi, Yuta, Terao, Chikashi, Matsuda, Fumihiko, Takao Fujii, Yamamoto, Kazuhiko, Meiko Takahashi, Akira Murasawa, Kubo, Michiaki, Tsukasa Matsubara, Mizuki, Shinichi, Hisashi Yamanaka, Mitsuhiro Iwahashi, Tsuneyo Mimori, Natsumeda, Masamitsu, Ezawa, Kazuhiko, Matsubara, Tsukasa, Shimizu, Masakazu, Masamitsu Natsumeda, Moritoshi Furu, Momohara, Shigeki, Okada, Yukinori, Keiko Myouzen, Atsuo Taniguchi, Suzuki, Akari, Furu, Moritoshi, Ryo Yamada, Ito, Hiromu, Murasawa, Akira, Motomu Hashimoto, Mimori, Tsuneyo, Katsunori Ikari, Yukinori Okada, Shigeki Momohara, Ikari, Katsunori, Funahashi, Keiko, Takahisa Kawaguchi, Hashimoto, Motomu, Nishina, Naoshi, Koichiro Ohmura, Fumihiko Matsuda, Myouzen, Keiko, Takahashi, Meiko, Kiyoshi Takasugi, Ohmura, Koichiro, Yamanaka, Hisashi, Naoshi Nishina, Yamada, Ryo, Taniguchi, Atsuo, Masakazu Shimizu, Yuta Kochi, Kazuhiko Ezawa, Takasugi, Kiyoshi, Fujii, Takao, Keiko Funahashi, Chikashi Terao, Tsutomu Takeuchi, Hiromu Ito, Kazuhiko Yamamoto, Shinichi Mizuki, Kawaguchi, Takahisa, Iwahashi, Mitsuhiro, Michiaki Kubo   +63 more
core   +1 more source

Synovial Fluid Cell Profiling Identifies Distinct Inflammatory Phenotypes in Late‐Onset Rheumatoid Arthritis and Polymyalgia Rheumatica

ACR Open Rheumatology
Objective Late‐onset rheumatoid arthritis (LORA) and polymyalgia rheumatica (PMR) can be difficult to distinguish, particularly in anti–citrullinated protein antibody (ACPA)‐negative patients.
Shigeru Tanaka, Takahiro Sugiyama, Shuhei Kameda, Tatsuro Takahashi, Masahiro Yasui, Yuki Hayashi, Tomoaki Ida, Yuhi Yoshida, Soichiro Kubota, Takashi Ito, Takahiro Kageyama, Daiki Nakagomi, Kei Ikeda, Shin‐Ichiro Kagami, Hiroshi Nakajima   +14 more
doaj   +1 more source