Results 121 to 130 of about 5,038 (172)

Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population

, 2017
Background HLA-DRB1 is the strongest susceptibility gene to rheumatoid arthritis (RA). HLA-DRB1 alleles showed significant non-additive and interactive effects on susceptibility to RA in the European population, but these effects on RA susceptibility ...
Soumya Raychaudhuri, Akari Suzuki, Kochi, Yuta, Terao, Chikashi, Mimori, Tsuneyo, Matsuda, Fumihiko, Katsunori Ikari, Yukinori Okada, Yamamoto, Kazuhiko, Kamatani, Yoichiro, Ikari, Katsunori, Kubo, Michiaki, Raychaudhuri, Soumya, Koichiro Ohmura, Hisashi Yamanaka, Fumihiko Matsuda, Tsuneyo Mimori, Yoichiro Kamatani, Ohmura, Koichiro, Yamanaka, Hisashi, Keitaro Matsuo, Taniguchi, Atsuo, Yuta Kochi, Okada, Yukinori, Atsuo Taniguchi, Chikashi Terao, Kazuhiko Yamamoto, Suzuki, Akari, Matsuo, Keitaro, Michiaki Kubo   +29 more
core   +1 more source

Rheumatoid factor and anti-cyclic citrullinated peptide antibody levels decline in rheumatoid arthritis patients treated with Janus kinase inhibitors or biological disease-modifying anti-rheumatic drugs

Journal of Rheumatic Diseases
Objective: We aimed to investigate the rate of decline in serum anti-cyclic citrullinated peptide antibody (ACPA) and rheumatoid factor (RF) levels in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis) compared with ...
Bo Young Kim, Ji-Won Kim, Hwajeong Lee, Sung-Hoon Park, Seong-Kyu Kim, Jung-Yoon Choe   +5 more
doaj   +1 more source

Sistemik sklerozda ACPA (Anti Citrullinated Protein Antibody)'nın prognostik değeri

, 2019
Sistemik Skleroz (SSc) iç organlar ve deride fibrozis ve küçük kan damarlarında vaskülopati ile seyreden otoimmün bir hastalıktır. Klinik olarak deride kalınlaşma, Raynaud fenomeni, pulmoner arteriyel hipertansiyon, pulmoner fibrozis ve başka visseral ...
TÜRKÇAPAR, Nuran (Tez Danışmanı), DALGIÇ, Günay Şahin (Yazar)   +1 more
core  

Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation

, 2017
Recent reports describe interactions between the two most prominent RA-related autoantibodies, RFs and ACPAs. The main aim of the present study was to investigate whether RFs preferentially interact with ACPA-IgG over non-ACPA IgG.
Ooijevaar-de Heer, Pleuni, Bentlage, Arthur E. H., Pleuni Ooijevaar-de Heer, Hans U Scherer, Theo Rispens, Toes, René E. M., Rispens, Theo, René E M Toes, Gillian Dekkers, Willem J J Falkenburg, Ayla C Kempers, Kempers, Ayla C., Dirkjan van Schaardenburg, Arthur E H Bentlage, van Schaardenburg, Dirkjan, Scherer, Hans U., Falkenburg, Willem J. J., Gestur Vidarsson, Dekkers, Gillian, Vidarsson, Gestur   +19 more
core   +1 more source

Associations of amino acid residues in the DPβ chains with ACPA(+)RA.

, 2018
(A) Association was established between ACPA(+)RA and controls by logistic regression analysis. (B) Conditional logistic regression analysis was performed to clarify whether each DPβ chain amino acid residue was independently associated with ACPA(+)RA ...
Hiroshi Furukawa (290179), Hajime Sano (12547), Masao Katayama (518771), Shomi Oka (290181), Naoshi Fukui (86346), Akiko Komiya (290188), Seiji Minota (2657893), Toshihiro Matsui (1917), Kota Shimada (152649), Shinichiro Tsunoda (574965), Shigeto Tohma (290204), Shoji Sugii (290183), Kiyoshi Migita (290200), Atsushi Hashimoto (290186), Satoshi Ito (12555), Katsuya Nagatani (5775395), Satoshi Shinohara (5010533), Koichiro Saisho (574964), Shouhei Nagaoka (290202), Akiko Suda (290201), Takeo Sato (164222)   +20 more
core   +1 more source

ACPA-Induced ATP release and K+ efflux trigger NLRP3 inflammasome activation in rheumatoid arthritis

Cell Communication and Signaling
Objectives Anti-citrullinated protein antibodies (ACPA) is one of the key inducers of the initiation and maintenance of the immune-inflammatory response in Rheumatoid arthritis (RA), yet evidence is lacking on how ACPA drives the inflammatory response ...
Li Cai, Kai Zhang, Jian Gao, Bing Xiao, Meng Li, Xiangyun Meng, Zhipeng Chen, Xiaoling Chen, Shixian Chen, Juan Li   +9 more
doaj   +1 more source

Serum anticyclic citrullinated protein antibody titers are correlated with the response to biological agents in patients with rheumatoid arthritis

Open Access Rheumatology: Research and Reviews, 2014
Ryo Takahashi, Sakiko Isojima, Masayu Umemura, Yoko Miura, Nao Oguro, Syo Ishii, Shinya Seki, Takahiro Tokunaga, Hiroyuki Tsukamoto, Hidekazu Furuya, Ryo Yanai, Tsuyoshi KasamaDivision of Rheumatology, Department of Medicine, Showa University School of ...
Takahashi R, Isojima S, Umemura M, Miura Y, Oguro N, Ishii S, Seki S, Tokunaga T, Tsukamoto H, Furuya H, Yanai R, Kasama T   +11 more
doaj  

The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis

, 2010
Background The presence of anti-citrullinated protein antibodies (ACPA) is a powerful predictive factor for the development and progression of rheumatoid arthritis (RA).
Verpoort, K.N., Huizinga, T.W.J., Goll, G.L., Kvien, T.K., Linden, M.P.M. van der, Voort, E.I.H. van der, Woude, D. van der, Helm-van Mil, A.H.M. van der, Syversen, S.W., Heijde, D.M.F.M. van der, Toes, R.E.M.   +10 more
core  

Structure of Francisella tularensis AcpA [PDF]

Journal of Biological Chemistry, 2006
Richard L. Felts, Thomas J. Reilly, John J. Tanner   +2 more
openaire   +1 more source

Response to the ACPA's Critique: Response

Environmental Health Perspectives, 1998
John Acquavella, Dennis Flaherty, Carol Burns, Michael Holsapple, Ian Kimber, Gregory Ladics, Scott Loveless, Abraham Tobia   +7 more
openaire   +1 more source