Results 81 to 90 of about 16,745 (200)

Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine. [PDF]

open access: yesPLoS ONE, 2012
Thiamine (Vitamin B1) is an essential vitamin that must be obtained from the diet for proper neurological function. At higher doses, thiamine and benfotiamine (S-benzoylthiamine O-monophosphate, BT)-a phosphorylated derivative of thiamine-have ...
Julie K Hurt   +6 more
doaj   +1 more source

La mediación penal [PDF]

open access: yes, 2015
En este trabajo se analiza la evolución de la mediación penal, su problemática, los delitos que podrían someterse a mediación, el desarrollo del procedimiento y sus ...
Mollar Piquer, María Pilar
core   +1 more source

Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. [PDF]

open access: yes, 2018
Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous ...
Damotte, Vincent   +2 more
core   +1 more source

Enhancing siRNA-based cancer therapy using a new pH-responsive activatable cell-penetrating peptide-modified liposomal system

open access: yesInternational Journal of Nanomedicine, 2017
Bai Xiang,1,* Xue-Li Jia,1,* Jin-Long Qi,2 Li-Ping Yang,1 Wei-Hong Sun,1 Xiao Yan,1 Shao-Kun Yang,1 De-Ying Cao,1 Qing Du,1 Xian-Rong Qi3 1Department of Pharmaceutics, School of Pharmaceutical Sciences, 2Department of Pharmacology, Hebei Medical ...
Xiang B   +9 more
doaj  

Core - Corona Model analysis of the Low Energy Beam Scan at RHIC (Relativistic Heavy Ion Collider) in Brookhaven (USA)

open access: yes, 2013
The centrality dependence of spectra of identified particles in collisions between ultrarelativistic heavy ions with a center of mass energy ($\sqrt{s}$) of 39 and 11.5 $AGeV$ is analyzed in the core - corona model.
Aichelin   +7 more
core   +5 more sources

Abstract A005: MMP FRET ACPP imaging of mammary tumors in a mouse model of postmenopausal obesity

open access: yesMolecular Cancer Research, 2013
Abstract Obesity in postmenopausal women is a risk factor for breast cancer. Since 25-30% of women in the USA are obese, the public health implications of obesity and breast cancer are immense. Activation of inflammatory pathways is one plausible mechanism underlying the association between obesity and increased breast cancer risk.
Crisp, Jessica L   +5 more
openaire   +3 more sources

Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid

open access: yesChemistry – A European Journal, Volume 31, Issue 34, June 17, 2025.
This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile   +4 more
wiley   +1 more source

Functional and evolutionary characterization of potential auxiliary metabolic genes of the global RNA virome

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
We generated the first comprehensive view of RNA viral auxiliary metabolic genes (AMGs), expanding the known functional type of AMGs by 75%. RNA viruses encode a remarkably high diversity of AMGs, spanning 25 distinct functional categories. Most of these genes are linked to environmental regulation and genetic information processing, with fewer ...
Yang Zhao   +4 more
wiley   +1 more source

Secondary materials from household waste and their position in the global market [PDF]

open access: yes, 2013
Bakalářská práce je zaměřena na problematiku materiálového využití komponent obsažených v komunálních odpadech. V práci jsou uvedeny základní pojmy odpadového hospodářství a zdroje dat, které pomáhají analyzovat součastnou situaci v oblasti nakládání s ...
Tesař, Jan
core  

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, Volume 599, Issue 8, Page 1159-1168, April 2025.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

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