Results 51 to 60 of about 406,782 (308)

Sensorimotor vs. Motor Upper Limb Therapy for Patients With Motor and Somatosensory Deficits: A Randomized Controlled Trial in the Early Rehabilitation Phase After Stroke

Frontiers in Neurology, 2020
Background: Somatosensory function plays an important role in motor learning. More than half of the stroke patients have somatosensory impairments in the upper limb, which could hamper recovery.Question: Is sensorimotor upper limb (UL) therapy of more ...
Nele De Bruyn, Leen Saenen, Liselot Thijs, Annick Van Gils, Eva Ceulemans, Bea Essers, Christophe Lafosse, Marc Michielsen, Hilde Beyens, Fabienne Schillebeeckx, Kaat Alaerts, Geert Verheyden   +11 more
doaj   +1 more source

The contribution of injury severity, executive and implicit functions to awareness of defi cits after traumatic brain injury (TBI) [PDF]

, 2010
Deficits in self-awareness are commonly seen after Traumatic Brain Injury (TBI) and adversely affect rehabilitative efforts, independence and quality of life (Ponsford, 2004).
Barker, Lynne, Morton, Nicholas
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Characterizing the evolution of oculomotor and vestibulo-ocular function over time in children and adolescents after a mild traumatic brain injury

Frontiers in Neurology, 2022
BackgroundImpairments to oculomotor (OM) and vestibulo-ocular reflex (VOR) function following pediatric mTBI have been demonstrated but are poorly understood.
Adrienne Crampton, Kathryn J. Schneider, Kathryn J. Schneider, Kathryn J. Schneider, Lisa Grilli, Mathilde Chevignard, Mathilde Chevignard, Mathilde Chevignard, Michal Katz-Leurer, Miriam H. Beauchamp, Miriam H. Beauchamp, Chantel Debert, Isabelle J. Gagnon, Isabelle J. Gagnon   +13 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Challenges in understanding the epidemiology of acquired brain injury in India. [PDF]

An acquired brain injury (ABI) is an injury to the brain, which is not hereditary, congenital, degenerative, or induced by birth trauma. In India, rapid urbanization, economic growth and changes in lifestyle have led to a tremendous increase in the ...
Goenka, Shifalika, Gudlavalleti, Aashrai SV, Kamalakannan, Suresh Kumar, Kuper, Hannah, Murthy Gudlavalleti, Venkata S   +4 more
core   +1 more source

Acceptance and commitment therapy delivered in a dyad after a severe traumatic brain injury: a feasibility study [PDF]

, 2018
Objective: There is a high prevalence of complex psychological distress after a traumatic brain injury but limited evidence of effective interventions.
Ciarrochi, Joseph V., Deane, Frank P., McLeod, Hamish J., Simpson, Grahame K., Whiting, Diane L.   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reorganization of functional connectivity as a correlate of cognitive recovery in acquired brain injury. [PDF]

, 2010
Cognitive processes require a functional interaction between specialized multiple, local and remote brain regions. Although these interactions can be strongly altered by an acquired brain injury, brain plasticity allows network reorganization to be ...
Aertsen, Alstott, Alvaro Bilbao, Bartolomei, Bartolomei, Beason-Held, Bennett, Bosma, Bosma, Bressler, Brookes, Bullmore, Butz, Campo, Cao, Cicerone, Cicerone, Cover, Cover, Damoiseaux, Dehaene, Douw, Fernando Maestú, Fingelkurts, Florence, Francisco del-Pozo, Gasser, Gladsojo, Golden, Gootjes, Grinsted, Guggisberg, Hadjipapas, Halgren, Halligan, Heaton, Hebb, Honey, Huan, Jaakkola, Jenkins, Katz, Kelly, Kilner, Kolb, Korzeniewska, Lee, Lehmanna, Leocani, Lewine, Lewine, Lishman, Lowe, Maindonald, Mallat, McCabe, Merzenich, Murias, Muñoz-Céspedes, Nakamura, Nazareth P. Castellanos, Nolte, Nudo, Nudo, Nuria Paúl, Olivier Demuynck, Pablo Campo, Palva, Percival, Pivik, Prigatano, Quigley, Reitan, Rholing, Ricardo Bajo, Ripley, Rosenzweig, Rubinov, Salvador, Schnitzler, Schreiber, Schretlen, Singer, Stam, Stam, Stam, Stam, Stam, Theiler, Tomás Ortiz, Tononi, Torrence, Tucha, Turner-Stokes, Varela, Victoria E. Ordóñez, von Stein, Wechsler, Wechsler, Wilson, Wilson, Witte, Édouard   +102 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source