The aspiration of precision glucocorticoid pharmacotherapy in immune-mediated diseases: where do we stand in integrating pharmacogenomics and biomarkers for individualized treatment? [PDF]
Front ImmunolColina M, Campana G.
europepmc +1 more source
Ethology, EarlyView.Corpses are repositories of information about the cause of death. The distress of the bereaved acts as an honest signal drawing conspecifics to the body, enabling them to learn quickly about the death, adapt their behaviour, and spread knowledge of threats across multiple social levels.
Jacob Dembitzer, Dror Ben‐Ami
wiley +1 more source
Drug Resistance in Multiple Myeloma: Tumor-Intrinsic Mechanisms and the Bone Marrow Microenvironment. [PDF]
Cell Biochem FunctChen Y, Huang W, Tang M, Wang X.
europepmc +1 more source
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Comprehensive analysis of factors to consider when using glucocorticoids for sCAP: A review. [PDF]
Medicine (Baltimore)Zhao T, Li J, Chen J, Wang J.
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Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
The FEBS Journal, EarlyView.MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
Cross-Talk Between Histamine H<sub>2</sub> Receptor and Glucocorticoid Receptor: Potential Implications in Acute Myeloid Leukemia Treatment. [PDF]
Pharmacol Res PerspectTorralba-Agu V +5 more
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Arteriosclerosis, Thrombosis and Vascular Biology, 1999 Paula J. Bray +8 more
semanticscholar +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source