Results 101 to 110 of about 8,451,399 (181)

Long QT syndrome in patients over 40 years of age: increased risk for LQTS-related cardiac events in patients with coronary disease.

, 2008
Previous studies of long QT syndrome (LQTS) have focused primarily on the clinical course of affected patients up to 40 years of age to avoid the confounding influence of acquired heart disease on LQTS-related cardiac events in this genetic disorder ...
Ackerman MJ, Goldenberg I, Qi M, Zhang L., Spazzolini C, Vincent GM, Towbin J, Sze E, SPAZZOLINI, CARLA, Kaufman E, PRIORI, SILVIA GIULIANA, SCHWARTZ, PETER, Locati E, Moss AJ, Benhorin J, International Long QT Syndrome Investigative G.r.o.u.p. Ackerman MJ, Robinson JL, Jons C, Zareba W, McNitt S, Napolitano C   +20 more
core   +1 more source

Structure–Activity Relationships of 1,4‐Benzodiazepines Inhibiting the Voltage‐Gated Potassium Channel KV7.1

Archiv der Pharmazie, Volume 359, Issue 10, October 2026.
KV7.1 antagonists hold potential for the treatment of diarrhea, reflux esophagitis, and hypoinsulinemia. To derive structure–activity relationships, the lead KV7.1 antagonist L768,673 was thoroughly modified in 1‐ and 3‐positions. The 3‐fluoropropyl‐substituted 1,4‐benzodiazepine showed promising KV7.1 inhibitory activity, qualifying it as a potential ...
Florian Roßner, Amy Methaq, Guiscard Seebohm, Bernhard Wünsch   +3 more
wiley   +1 more source

Clarithromycin-Induced Long QT Syndrome: A Case Report.

, 2012
Long QT syndrome develops for a number of reasons. The number of non-antiarrhythmic drugs reported to induce QT interval prolongation with or without torsade de pointes continues to increase.
Cetin, Mecnun, Tanrverdi, SEMA, Özen S., Yilidrimer M., COŞKUN, ŞENOL, Coskun S., Yilidrimer, Munevver, Tanrverdi S., YıLDıRıMER, M, Özen, Serkan, COSKUN, S, Cetin M., OZEN, S, TANRıVERDI, Selami   +13 more
core   +2 more sources

Application of Electromechanical Window Negativity as an Arrhythmia Risk Correlate in Acquired Long QT Syndrome. [PDF]

JACC Case Rep, 2021
Munshi F, Fontaine JM.
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, Volume 67, Issue 10, Page 5075-5125, October 2026.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. [PDF]

HeartRhythm Case Rep, 2022
Déléaval M, Burri H, Bakelants E.
europepmc   +1 more source

Charcot-Marie-Tooth type 1a in a child with Long QT syndrome [PDF]

, 2008
Charcot-Marie-Tooth disease (CMTD) is a hereditary demyelinating peripheral neuropathy clinically presenting with sensory and motor defects, but rarely affecting cardiac function.
Bassi MT, Trabacca A., De Rinaldis M, Bresolin N, Losito L, Gennaro L, Bloise R, PRIORI, SILVIA GIULIANA   +7 more
core  

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

Epilepsia, Volume 67, Issue 10, Page 5227-5242, October 2026.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan   +18 more
wiley   +1 more source

[Congenital long QT syndrome].

, 1998
International audienceSEVERAL FORMS: Congenital long QT syndrome is a clinically (with and without deafness) and genetically (recessive or dominant autosomal inheritance) heterogeneous entity characterized by a long QT interval on the ECG associated with
Neyroud, N, Guicheney, P, Coumel, P, Casasoprana, A, Denjoy, I, Lupoglazoff, J   +5 more
core   +1 more source

Case report: A 56-year-old woman presenting with torsades de pointes and cardiac arrest associated with levosimendan administration and underlying congenital long QT syndrome type 1

Heliyon
Torsades de Pointes (TdP) is a malignant polymorphic ventricular tachycardia with heart rate corrected QT interval (QTc) prolongation, which may be attributed to congenital and acquired factors.
Fengyan Zha, Xing Li, Hui Yin, Di Huang, Yu Du, Chuzhi Zhou   +5 more
doaj   +1 more source