Results 121 to 130 of about 25,450 (246)

Drug-induced life-threatening arrhythmias and sudden cardiac death: A clinical perspective of long QT, short QT and Brugada syndromes

open access: yesRevista Portuguesa de Cardiologia, 2018
Sudden cardiac death is a major public health challenge, which can be caused by genetic or acquired structural or electrophysiological abnormalities. These abnormalities include hereditary channelopathies: long QT, short QT and Brugada syndromes.
Diogo Ramalho, João Freitas
doaj   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

open access: yesThe Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary   +5 more
wiley   +1 more source

Erg currents support electrical bursting in murine anterior pituitary corticotrophs

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Anterior pituitary corticotrophs are a central component of the hypothalamic‐pituitary‐adrenal (HPA) axis that controls the release of glucocorticoids from the adrenal gland in response to stress. The hypothalamic secretagogue corticotrophin releasing hormone (CRH) promotes electrical bursting of mouse anterior pituitary ...
Sooraj V. Nair   +5 more
wiley   +1 more source

The Long QT Syndrome

open access: yesIndian Pacing and Electrophysiology Journal, 2002
The Long QT syndrome (LQTS) can be inherited or acquired and is of particular interest and concern at present. Patients with LQTS are predisposed to the ventricular tachyarrhythmia torsade de pointes (TdP) which causes syncope and sudden death. Inherited
G. Michael Vincent
doaj  

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato   +3 more
wiley   +1 more source

The long-QT syndrome: A silent killer [PDF]

open access: yes, 2010
Introduction: Sudden cardiac death is a striking phenomenon, affecting seemingly healthy individuals without warning. The long-QT syndrome is a common cause of sudden cardiac death that can either be inherited or acquired.
Crowley, Claire
core   +1 more source

Digital genetic counseling services for cascade cardiogenetic testing

open access: yesJournal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Digital interventions are potentially promising to improve accessibility and efficiency of genetic counseling services. However, current literature on user perspectives toward digital tools for cascade testing is limited. Therefore, this focus‐group study aimed to gain insights into the attitude and perspectives of probands, at‐risk relatives (
Marlies N. van Lingen   +8 more
wiley   +1 more source

Prevalence and risk factors for acquired long QT syndrome in the emergency department: a retrospective observational study. [PDF]

open access: yesWorld J Emerg Med, 2023
Fernandes DA   +7 more
europepmc   +1 more source

Genotype-Phenotype Relationships in Long QT Syndrome : Role of Mental Stress, Adrenergic Activity and a Common KCNH2 Polymorphism [PDF]

open access: yes, 2006
Long QT syndrome is a congenital or acquired arrhythmic disorder which manifests as a prolonged QT-interval on the electrocardiogram and as a tendency to develop ventricular arrhythmias which can lead to sudden death.
Paavonen, Kristian
core  

Efficacy and safety of 2–4 mg brexpiprazole in the management of schizophrenia: A systematic review and meta‐analysis

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
This graphical summary illustrates the efficacy and safety of brexpiprazole (2–4 mg) in patients with schizophrenia. The meta‐analysis demonstrates significant improvement in clinical outcomes, with reductions in Positive and Negative Syndrome Scale (PANSS) and Clinical Global Impression ‐ Severity scale (CGI‐S) scores, indicating better symptom ...
Sher Bano   +14 more
wiley   +1 more source

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