Results 121 to 130 of about 45,337 (219)

The Long QT Syndrome

Indian Pacing and Electrophysiology Journal, 2002
The Long QT syndrome (LQTS) can be inherited or acquired and is of particular interest and concern at present. Patients with LQTS are predisposed to the ventricular tachyarrhythmia torsade de pointes (TdP) which causes syncope and sudden death. Inherited
G. Michael Vincent
doaj  

PO-05-161 ACQUIRED LONG QT SYNDROME IN SEPSIS-INDUCED MYOCARDIAL INJURY: INVESTIGATION ON CLINICAL CHARACTERISTICS AND MECHANISM VIA ION CHANNEL REPROGRAMMING [PDF]

, 2023
Weizhuo Liu, Shen Zhang, Xiaoyu Guo, Nanqing Xiong, Jian Li, Bin He   +5 more
openalex   +1 more source

Facilitation of I Kr current by some hERG channel blockers suppresses early afterdepolarizations. [PDF]

, 2019
Drug-induced block of the cardiac rapid delayed rectifying potassium current (I Kr), carried by the human ether-a-go-go-related gene (hERG) channel, is the most common cause of acquired long QT syndrome.
Chen, I-Shan, Furutani, Kazuharu, Handa, Kenichiro, Kurachi, Yoshihisa, Sack, Jon T, Tsumoto, Kunichika, Yamakawa, Yuko   +6 more
core   +1 more source

Ventricular Fibrillation Caused by a Low-Rate Pacemaker

Forbes Tıp Dergisi
After undergoing surgery for a perimembranous ventricular septal defect and discrete membrane resection, a 7-year-old patient developed complete atrioventricular block and received an epicardial pacemaker.
Hüseyin YILDIZ, Ayşe SÜLÜ, Osman BAŞPINAR   +2 more
doaj   +1 more source

P4477Pi3kgamma inhibition rescues mice from acute cardiac contractile dysfunction, acquired long QT syndrome (acLQTS) and sudden death caused by calcineurin inhibitors [PDF]

, 2017
B. Ndongson Dongmo, Lise Román Moltzau, Kjetil Wessel Andressen, M. Baretta, Alessandra Ghigo, Michael Brodhun, Eugene Z. Hirsch, Sm Coldewey, Reinhard Bauer, Finn Olav Levy   +9 more
openalex   +1 more source

Long QT Syndrome With Drugs Used in the Management of Arrhythmias: A Systematic Review

Cureus
Long QT syndrome (LQTS) is a severe cardiac disorder characterized by an abnormally prolonged QTc interval on an electrocardiogram (ECG), which can result in life-threatening irregular heart rhythms.
Shenel A Khan, Soniya Emmanuel, Vivig Shantha Kumar, Resheek Nerella, Basim Shaman Ameen, Dev Patel, Jabez David John, Ranita Bodepudi, Saniya Seher, Sai Sri Penumetcha   +9 more
semanticscholar   +1 more source

Molecular and clinical determinants of drug-induced long QT syndrome: an iatrogenic channelopathy. [PDF]

, 2004
More than 70 drugs present on the Swiss market can cause drug-induced long QT syndrome (LQTS), which is associated with torsades de pointes (TdP) arrhythmias, potentially leading to sudden cardiac death. Basic and clinical investigations performed during
Abriel, H., Biollaz, J., Buclin, T., Gavillet, B., Kappenberger, L., Keller, D.I., Schläpfer, J., Stoller, R.   +7 more
core  

Antiarrhythmic effect of Vernakalant due to reduction of dispersion of repolarization and suppression of early afterdepolarizations in a rabbit model of acquired long-QT-syndrome [PDF]

, 2013
Peter Milberg, C. Clauss, Lars Eckardt, Gerrit Frommeyer   +3 more
openalex   +1 more source

Case report: A 56-year-old woman presenting with torsades de pointes and cardiac arrest associated with levosimendan administration and underlying congenital long QT syndrome type 1

Heliyon
Torsades de Pointes (TdP) is a malignant polymorphic ventricular tachycardia with heart rate corrected QT interval (QTc) prolongation, which may be attributed to congenital and acquired factors.
Fengyan Zha, Xing Li, Hui Yin, Di Huang, Yu Du, Chuzhi Zhou   +5 more
doaj   +1 more source

Early LQT2 Nonsense Mutation Generates N-Terminally Truncated hERG Channels with Altered Gating Properties by the Reinitiation of Translation

, 2012
Mutations in the human ether-a-go-go-related gene (hERG) result in long QT syndrome type 2 (LQT2). The hERG gene encodes a K+ channel that contributes to the repolarization of the cardiac action potential.
Gong, Qiuming, Packer, Jonathan D., Stump, Matthew R., Zhou, Zhengfeng   +3 more
core   +1 more source