Results 191 to 200 of about 28,434 (232)

The interactions of Pu22 G-quadruplex, derived from <i>c-MYC</i> promoter sequence, with antitumor acridine derivatives-An NMR/MD combined study. [PDF]

open access: yesMol Ther Nucleic Acids
Laskowski T   +7 more
europepmc   +1 more source

Biological and Teratogenic Evaluations of Nitrogen Heterocycles for Anticancer Therapy. [PDF]

open access: yesPharmaceuticals (Basel)
Dos Santos JC   +12 more
europepmc   +1 more source

Nickel‐asparagine complex fixed on a magnetic substrate as a precursor for preparing substituted acridines

Applied organometallic chemistry, 2023
In this work, an efficient, novel, retrievable, and magnetic heterogeneous nanocatalyst, Fe3O4@CPTMS@Asp@Ni was successfully fabricated using Fe3O4 nanoparticles as the core that were coated with surfactant and 3‐chloropropyltrimethoxysilan and deposited
Maryam Abbaszadehghan   +3 more
semanticscholar   +1 more source

A Review on Acridines as Antiproliferative Agents.

Mini-Reviews in Medical Chemistry, 2022
Acridine derivatives have been thoroughly investigated and discovered to have multitarget qualities, inhibiting topoisomerase enzymes that regulate topological changes in DNA and interfering with DNA's vital biological function.
B. Aparna   +4 more
semanticscholar   +1 more source

9-Substituted acridines as effective corrosion inhibitors for mild steel: electrochemical, surface morphology, and computational studies

New Journal of Chemistry, 2020
The inhibition performance and mechanism of mild steel in hydrochloric acid for 9-substituted acridines were studied for the first time.
Weiwei Zhang   +5 more
semanticscholar   +1 more source

Tert-butyl bromide promoted intramolecular cyclization of 2-arylamino phenyl ketones and its combination with Cu-catalyzed C-N coupling: synthesis of acridines at room temperature.

Journal of Organic Chemistry, 2020
Herein, a facile intramolecular cyclization of 2-arylamino phenyl ketones is established to supersede the traditional high temperature, strong acidic conditions and achieve 9-substituted acridines, by virtue of the combination of 2,2,2-trifluoroethanol ...
Zifeng Cao   +6 more
semanticscholar   +1 more source

A new look at 9‐substituted acridines with various biological activities

Journal of Applied Toxicology, 2020
Heterocycles have long been the focus of intensive study in attempts to develop novel therapeutic compounds, and acridine, a polynuclear nitrogen molecule containing a heterocycle, has attracted a considerable amount of scientific attention.
M. Kožurková   +2 more
semanticscholar   +1 more source

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