Results 1 to 10 of about 53,333 (203)

Derivatives Incorporating Acridine, Pyrrole, and Thiazolidine Rings as Promising Antitumor Agents

Molecules, 2023
Derivatives combining acridine, pyrrole, and thiazolidine rings have emerged as promising candidates in the field of antitumor drug discovery. This paper aims to highlight the importance of these three structural motifs in developing potent and selective
Monika Garberová, Ivan Potočňák, Monika Tvrdoňová, Monika Majirská, Martina Bago-Pilátová, Slávka Bekešová, Andrej Kováč, Peter Takáč, Krutika Khiratkar, Zuzana Kudličková, Ján Elečko, Mária Vilková   +11 more
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New Boron Containing Acridines: Synthesis and Preliminary Biological Study

Molecules, 2023
The synthesis of the first conjugates of acridine with cobalt bis(dicarbollide) are reported. A novel 9-azido derivative of acridine was prepared through the reaction of 9-methoxyacridine with N3CH2CH2NH2, and its solid-state molecular structure was ...
Anna A. Druzina, Nadezhda V. Dudarova, Ivan V. Ananyev, Anastasia A. Antonets, Dmitry N. Kaluzhny, Alexey A. Nazarov, Igor B. Sivaev, Vladimir I. Bregadze   +7 more
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A Novel Thiosemicarbazide-Based Fluorescent Chemosensor for Hypochlorite in Near-Perfect Aqueous Solution and Zebrafish

Chemosensors, 2021
A novel thiosemicarbazide-based fluorescent sensor (AFC) was developed. It was successfully applied to detect hypochlorite (ClO−) with fluorescence quenching in bis-tris buffer.
Minji Lee, Donghwan Choe, Soyoung Park, Hyeongjin Kim, Soomin Jeong, Ki-Tae Kim, Cheal Kim   +6 more
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A Facile and Catalyst-free Synthesis of Hexahydroacridine-1,8(2H,5H )-dione and Octahydroacridin-10(1H )-yl)thiourea Derivatives: Inter- and Intramolecular Aza-Michael addition

Heterocyclic Communications, 2020
An easy and convenient technique for the one-pot synthesis of novel compounds of hexahydroacridine-1,8(2H,5H)-dione and octahydroacridin-10(1H)-yl) thiourea derivatives has been developed by the reaction of the octahydro-1H-xanthenes with hydroxylamine ...
Pesyan Nader Noroozi, Akhteh Narmin, Batmani Hana, Anıl Barış, Şahin Ertan   +4 more
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3-Methoxy-5-methyl-12-phenylbenzacridinium Iodide

Molbank, 2022
N-alkylacridinium derivatives are some of the most popular azo dye templates. Herein, we report the synthesis of 3-methoxy-5-methyl-12-phenylbenzacridinium iodide (MMPBAI) via N-alkylation. The structure of MMPBAI was elucidated using 1H Nuclear magnetic
Malokhat Uktamova, Rintaro Koga, Fotima Mukhamedjonova, Tursunali Kholikov, Bakhtiyor Ibragimov, Kohei Torikai, Khamid Khodjaniyazov   +6 more
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Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity

Pathogens, 2021
In the last few years, increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain unsatisfactory.
Iwona Gabriel, Kamila Rząd, Ewa Paluszkiewicz, Katarzyna Kozłowska-Tylingo   +3 more
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Acridine as an Anti-Tumour Agent: A Critical Review

Molecules, 2022
This review summarized the current breakthroughs in the chemistry of acridines as anti-cancer agents, including new structural and biologically active acridine attributes.
Potlapati Varakumar, Kalirajan Rajagopal, Baliwada Aparna, Kannan Raman, Gowramma Byran, Clara Mariana Gonçalves Lima, Salma Rashid, Mohammed H. Nafady, Talha Bin Emran, Sławomir Wybraniec   +9 more
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Utilizing a Spiro Core with Acridine- and Phenothiazine-Based New Hole Transporting Materials for Highly Efficient Green Phosphorescent Organic Light-Emitting Diodes

Molecules, 2018
Two new hole transporting materials, 2,7-bis(9,9-diphenylacridin-10(9H)-yl)-9,9′ spirobi[fluorene] (SP1) and 2,7-di(10H-phenothiazin-10-yl)-9,9′-spirobi[fluorene] (SP2), were designed and synthesized by using the Buchwald–Hartwig coupling reaction with a
Ramanaskanda Braveenth, Il-Ji Bae, Ji-Hun Han, Wu Qiong, Guk Seon, Kanthasamy Raagulan, Kihun Yang, Young Hee Park, Miyoung Kim, Kyu Yun Chai   +9 more
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Comparative Study Regarding the Properties of Methylene Blue and Proflavine and Their Optimal Concentrations for In Vitro and In Vivo Applications

Diagnostics, 2020
Methylene blue and proflavine are fluorescent dyes used to stain nucleic acid from the molecular level to the tissue level. Already clinically used for sentinel node mapping, detection of neuroendocrine tumors, methemoglobinemia, septic shock, ifosfamide-
Maria-Eliza Nedu, Mihaela Tertis, Cecilia Cristea, Alexandru Valentin Georgescu   +3 more
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Crystal Structure of a New 1:1 Acridine-Diclofenac Salt, Obtained with High Yield by a Mechanochemical Approach

Crystals, 2022
The liquid-assisted grinding (LAG) approach was exploited to efficiently produce a new salt cocrystal with a minimum expenditure of reagents and energy, with possible application in the pharmaceutical field.
Artur Mirocki, Eleonora Conterosito, Luca Palin, Artur Sikorski, Marco Milanesio, Mattia Lopresti   +5 more
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