Results 1 to 10 of about 69,258 (233)

Acridine form IX [PDF]

Acta Crystallographica Section E: Crystallographic Communications, 2019
We report a new polymorph of acridine, C13H9N, denoted form IX, obtained as thin needles by slow evaporation of a toluene solution. The structure was solved and refined from powder X-ray data. The structures of five unsolvated forms were previously known,
Peter W. Stephens, Einat Schur, Saul H. Lapidus, Joel Bernstein   +3 more
doaj   +3 more sources

4,4′-(Acridine-2,7-diyl)bis(2-methylbut-3-yn-2-ol) [PDF]

IUCrData
The title acridine derivative, C23H21NO2, which has two 2-methylbut-3-yn-2-ol moieties at the 2,7-positions, was synthesized by Sonogashira coupling reaction. In the crystal, a columnar structure is formed by the π–π stacking of acridine units.
Masaki Yamamura, Seira Ikuma, Tatsuya Nabeshima   +2 more
doaj   +2 more sources

Acridine 0.75-hydrate [PDF]

Acta Crystallographica Section E, 2011
The title compound, C13H9N·0.75H2O was obtained during a study of the polymorphic system of acridine, by slow evaporation from an ethanol–water solution.
Andreas Lemmerer, Joel Bernstein, Einat Schur, Radion Vainer   +3 more
doaj   +3 more sources

Biological and Teratogenic Evaluations of Nitrogen Heterocycles for Anticancer Therapy [PDF]

Pharmaceuticals
Background: Heterocycle compounds with acridine, quinoline, indole, and pyridine nuclei are potentially active for anticancer activity since they can promote inhibition of vital enzymes, decreasing cell survival after binding to biomolecules.
Jéssica Celerino dos Santos, Josival Emanuel Ferreira Alves, Rafael David Souto de Azevedo, Josefa Gerlane da Silva, Maria Regina de Oliveira Silva, Lucia Patrícia Bezerra Gomes da Silva, Caio Victor Silva Soares, Jamire Muriel da Silva, Nabuêr Francieli da Silva, Jamerson Ferreira de Oliveira, Maria do Carmo Alves de Lima, Ricardo Olímpio de Moura, Sinara Mônica Vitalino de Almeida   +12 more
doaj   +2 more sources

Derivatives Incorporating Acridine, Pyrrole, and Thiazolidine Rings as Promising Antitumor Agents

Molecules, 2023
Derivatives combining acridine, pyrrole, and thiazolidine rings have emerged as promising candidates in the field of antitumor drug discovery. This paper aims to highlight the importance of these three structural motifs in developing potent and selective
Monika Garberová, Ivan Potočňák, Monika Tvrdoňová, Monika Majirská, Martina Bago-Pilátová, Slávka Bekešová, Andrej Kováč, Peter Takáč, Krutika Khiratkar, Zuzana Kudličková, Ján Elečko, Mária Vilková   +11 more
doaj   +1 more source

New Boron Containing Acridines: Synthesis and Preliminary Biological Study

Molecules, 2023
The synthesis of the first conjugates of acridine with cobalt bis(dicarbollide) are reported. A novel 9-azido derivative of acridine was prepared through the reaction of 9-methoxyacridine with N3CH2CH2NH2, and its solid-state molecular structure was ...
Anna A. Druzina, Nadezhda V. Dudarova, Ivan V. Ananyev, Anastasia A. Antonets, Dmitry N. Kaluzhny, Alexey A. Nazarov, Igor B. Sivaev, Vladimir I. Bregadze   +7 more
doaj   +1 more source

A Novel Thiosemicarbazide-Based Fluorescent Chemosensor for Hypochlorite in Near-Perfect Aqueous Solution and Zebrafish

Chemosensors, 2021
A novel thiosemicarbazide-based fluorescent sensor (AFC) was developed. It was successfully applied to detect hypochlorite (ClO−) with fluorescence quenching in bis-tris buffer.
Minji Lee, Donghwan Choe, Soyoung Park, Hyeongjin Kim, Soomin Jeong, Ki-Tae Kim, Cheal Kim   +6 more
doaj   +1 more source

A Facile and Catalyst-free Synthesis of Hexahydroacridine-1,8(2H,5H )-dione and Octahydroacridin-10(1H )-yl)thiourea Derivatives: Inter- and Intramolecular Aza-Michael addition

Heterocyclic Communications, 2020
An easy and convenient technique for the one-pot synthesis of novel compounds of hexahydroacridine-1,8(2H,5H)-dione and octahydroacridin-10(1H)-yl) thiourea derivatives has been developed by the reaction of the octahydro-1H-xanthenes with hydroxylamine ...
Pesyan Nader Noroozi, Akhteh Narmin, Batmani Hana, Anıl Barış, Şahin Ertan   +4 more
doaj   +1 more source

3-Methoxy-5-methyl-12-phenylbenzacridinium Iodide

Molbank, 2022
N-alkylacridinium derivatives are some of the most popular azo dye templates. Herein, we report the synthesis of 3-methoxy-5-methyl-12-phenylbenzacridinium iodide (MMPBAI) via N-alkylation. The structure of MMPBAI was elucidated using 1H Nuclear magnetic
Malokhat Uktamova, Rintaro Koga, Fotima Mukhamedjonova, Tursunali Kholikov, Bakhtiyor Ibragimov, Kohei Torikai, Khamid Khodjaniyazov   +6 more
doaj   +1 more source

Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity

Pathogens, 2021
In the last few years, increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain unsatisfactory.
Iwona Gabriel, Kamila Rząd, Ewa Paluszkiewicz, Katarzyna Kozłowska-Tylingo   +3 more
doaj   +1 more source