Results 31 to 40 of about 69,258 (233)

Formation of viable cell fragments by treatment with colchicine [PDF]

, 1976
Time-lapse cinematography of human fibroblasts revealed that mitotic cells separated into numerous cell fragments containing varying amounts of chromatin and cytoplasm when treated with colchicine.
Abercrombie, Becker, Borisy, C. Cremer, C. Zorn, Cremer, Ege, Ege, Ege, Goldman, Hayflick, J. Zimmer, Phillips, Phillips, Stubblefield, T. Cremer, Van den Brenk, Wessels, Zorn   +18 more
core   +1 more source

Acridine Based Small Molecular Hole Transport Type Materials for Phosphorescent OLED Application

Molecules, 2021
Two small molecular hole-transporting type materials, namely 4-(9,9-dimethylacridin-10(9H)-yl)-N-(4-(9,9-dimethylacridin-10(9H)-yl)phenyl)-N-phenylaniline (TPA-2ACR) and 10,10′-(9-phenyl-9H-carbazole-3,6-diyl)bis(9,9-dimethyl-9,10-dihydroacridine) (PhCAR-
Ramanaskanda Braveenth, Keunhwa Kim, Il-Ji Bae, Kanthasamy Raagulan, Bo Mi Kim, Miyoung Kim, Kyu Yun Chai   +6 more
doaj   +1 more source

Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]

, 2016
Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A., Diez, Berenice Andrea, Fukuda, Haydee, Teijo, Maria Julieta   +3 more
core   +2 more sources

Electron-Deficient Acetylenes as Three-Modal Adjuvants in S_N^H Reaction of Pyridinoids with Phosphorus Nucleophiles

Molecules, 2021
Publications covering a new easy metal-free functionalization of pyridinoids (pyridines, quinolines, isoquinolines, acridine) under the action of the system of electron-deficient acetylenes (acetylenecarboxylic acid esters, acylacetylenes)/P-nucleophiles
Boris A. Trofimov, Pavel A. Volkov, Anton A. Telezhkin   +2 more
doaj   +1 more source

Acridine Based N-Acylhydrazone Derivatives as Potential Anticancer Agents: Synthesis, Characterization and ctDNA/HSA Spectroscopic Binding Properties

Molecules, 2022
A series of novel acridine N-acylhydrazone derivatives have been synthesized as potential topoisomerase I/II inhibitors, and their binding (calf thymus DNA—ctDNA and human serum albumin—HSA) and biological activities as potential anticancer agents on ...
Mária Vilková, Monika Hudáčová, Nikola Palušeková, Rastislav Jendželovský, Miroslav Almáši, Tibor Béres, Peter Fedoročko, Mária Kožurková   +7 more
doaj   +1 more source

Molecular Recognition Studies on Naphthyridine Derivatives

Molecules, 2010
The association constants Kb of three hosts I–III designed to have both enhanced hydrogen bonding donor strength and conformational preorganization with biotin analogues 1–5 are reported.
José Carlos Iglesias-Sánchez, Dolores Santa María, Rosa M. Claramunt, José Elguero   +3 more
doaj   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

Archaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares, Eriola Jakoel, Ron Be’eri, Oded Lipschits, Ronny Neumann, Yuval Gadot   +5 more
wiley   +1 more source

Supramolecular interactions in a 1:1 co-crystal of acridine and 3-chlorothiophene-2-carboxylic acid

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the title co-crystal, C5H3ClO2S·C13H9N, the components interact with each other via an O—H...N hydrogen bond. Acridine–acridine stacking, thiophene–thiophene stacking and acridine–thiophene C—H...π interactions also occur in the crystal.
Olakkandiyil Prajina, Packianathan Thomas Muthiah, Franc Perdih   +2 more
doaj   +1 more source

Combination of small molecule microarray and confocal microscopy techniques for live cell staining fluorescent dye discovery [PDF]

, 2013
Discovering new fluorochromes is significantly advanced by high-throughput screening (HTS) methods. In the present study a combination of small molecule microarray (SMM) prescreening and confocal laser scanning microscopy (CLSM) was developed in order to
Attila Bokros, Begüm Peksel, Bhavyashree Suresh, Eszter Molnár, Ferhan Ayaydin, Gabriella Fábián, Liliána Z. Fehér, László G. Puskás, Pradeep Kumar Reddy Cingaram, Soujanya Kuntam, Ágnes Medgyesi   +10 more
core   +2 more sources

Cytosolic Glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease [PDF]

, 2019
A new paradigm for Niemann-Pick C disease is presented where lysosomal storage leads to a deficit in cytoplasmic glucosylceramide (GlcCer) where it performs important functions.
Bhardwaj, Meenakshi, Haberkant, Per, Schmid, Ralf, Sillence, Daniel J., Tongue, Paige, Wheeler, S.   +5 more
core   +1 more source