Results 21 to 30 of about 40,079 (224)

The Crystal Structure and Intermolecular Interactions in Fenamic Acids–Acridine Complexes

open access: yesMolecules, 2021
In order to improve pharmaceutical properties of drugs, complexes are synthesized as combinations with other chemical substances. The complexes of fenamic acid and its derivatives, such as mefenamic-, tolfenamic- and flufenamic acid, with acridine were ...
Marta S. Krawczyk   +2 more
doaj   +1 more source

‘Acridines’ as New Horizons in Antifungal Treatment

open access: yesMolecules, 2020
Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide.
Iwona Gabriel
doaj   +1 more source

Novel acridine-based thiosemicarbazones as ‘turn-on' chemosensors for selective recognition of fluoride anion: a spectroscopic and theoretical study [PDF]

open access: yesRoyal Society Open Science, 2018
New thiosemicarbazide-linked acridines 3a–c were prepared and investigated as chemosensors for the detection of biologically and environmentally important anions. The compounds 3a–c were found selective for fluoride (F−) with no affinity for other anions,
Ibanga Okon Isaac   +9 more
doaj   +1 more source

Acridine Based Small Molecular Hole Transport Type Materials for Phosphorescent OLED Application

open access: yesMolecules, 2021
Two small molecular hole-transporting type materials, namely 4-(9,9-dimethylacridin-10(9H)-yl)-N-(4-(9,9-dimethylacridin-10(9H)-yl)phenyl)-N-phenylaniline (TPA-2ACR) and 10,10′-(9-phenyl-9H-carbazole-3,6-diyl)bis(9,9-dimethyl-9,10-dihydroacridine) (PhCAR-
Ramanaskanda Braveenth   +6 more
doaj   +1 more source

Electron-Deficient Acetylenes as Three-Modal Adjuvants in SNH Reaction of Pyridinoids with Phosphorus Nucleophiles

open access: yesMolecules, 2021
Publications covering a new easy metal-free functionalization of pyridinoids (pyridines, quinolines, isoquinolines, acridine) under the action of the system of electron-deficient acetylenes (acetylenecarboxylic acid esters, acylacetylenes)/P-nucleophiles
Boris A. Trofimov   +2 more
doaj   +1 more source

Molecular Recognition Studies on Naphthyridine Derivatives

open access: yesMolecules, 2010
The association constants Kb of three hosts I–III designed to have both enhanced hydrogen bonding donor strength and conformational preorganization with biotin analogues 1–5 are reported.
José Carlos Iglesias-Sánchez   +3 more
doaj   +1 more source

Acridine Based N-Acylhydrazone Derivatives as Potential Anticancer Agents: Synthesis, Characterization and ctDNA/HSA Spectroscopic Binding Properties

open access: yesMolecules, 2022
A series of novel acridine N-acylhydrazone derivatives have been synthesized as potential topoisomerase I/II inhibitors, and their binding (calf thymus DNA—ctDNA and human serum albumin—HSA) and biological activities as potential anticancer agents on ...
Mária Vilková   +7 more
doaj   +1 more source

Supramolecular interactions in a 1:1 co-crystal of acridine and 3-chlorothiophene-2-carboxylic acid

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
In the title co-crystal, C5H3ClO2S·C13H9N, the components interact with each other via an O—H...N hydrogen bond. Acridine–acridine stacking, thiophene–thiophene stacking and acridine–thiophene C—H...π interactions also occur in the crystal.
Olakkandiyil Prajina   +2 more
doaj   +1 more source

An Acridine-Based Fluorescent Sensor for Monitoring ClO in Water Samples and Zebrafish

open access: yesSensors, 2020
A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared.
Su Chan Lee   +5 more
doaj   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

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