Results 21 to 30 of about 53,333 (203)
Engineering, 2015 The emergence of multidrug-resistant bacteria creates an urgent need for alternative antibiotics with new mechanisms of action. In this study, we synthesized a novel type of antimicrobial agent, Acr3-NLS, by conjugating hydrophobic acridines to the N ...
Wei Zhang +7 more
doaj +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
Synthesis of nitro acridine derivatives. [PDF]
, 1926 At the present time there is not much known about derivatives of acridine. However, there are derivatives of acridine which are important as dyes, drugs and antiseptics.
Friedrich, Martin
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Acta Crystallographica Section E, 2014 The title compound C25H29BrClNO4, comprises a 3,3,6,6-tetramethyltetrahydroacridine-1,8-dione ring system that carries a hydroxyethyl substituent on the acridine N atom and a 3-bromo-5-chloro-2-hydroxyphenyl ring on the central methine C atom of the ...
Antar A. Abdelhamid +2 more
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The Crystal Structure and Intermolecular Interactions in Fenamic Acids–Acridine Complexes
Molecules, 2021 In order to improve pharmaceutical properties of drugs, complexes are synthesized as combinations with other chemical substances. The complexes of fenamic acid and its derivatives, such as mefenamic-, tolfenamic- and flufenamic acid, with acridine were ...
Marta S. Krawczyk +2 more
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Acridine and its derivatives. [PDF]
, 1926 Acridine was discovered by Graebe and Caro who found that it accompanied the crude anthracene obtained from coal-tar. For its isolation, the portion of the tar distilling at 300°- 360° C.
Vianna, Altemiro Ferreira
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‘Acridines’ as New Horizons in Antifungal Treatment
Molecules, 2020 Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide.
Iwona Gabriel
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Novel acridine-based thiosemicarbazones as ‘turn-on' chemosensors for selective recognition of fluoride anion: a spectroscopic and theoretical study [PDF]
Royal Society Open Science, 2018 New thiosemicarbazide-linked acridines 3a–c were prepared and investigated as chemosensors for the detection of biologically and environmentally important anions. The compounds 3a–c were found selective for fluoride (F−) with no affinity for other anions,
Ibanga Okon Isaac +9 more
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Acridine Based Small Molecular Hole Transport Type Materials for Phosphorescent OLED Application
Molecules, 2021 Two small molecular hole-transporting type materials, namely 4-(9,9-dimethylacridin-10(9H)-yl)-N-(4-(9,9-dimethylacridin-10(9H)-yl)phenyl)-N-phenylaniline (TPA-2ACR) and 10,10′-(9-phenyl-9H-carbazole-3,6-diyl)bis(9,9-dimethyl-9,10-dihydroacridine) (PhCAR-
Ramanaskanda Braveenth +6 more
doaj +1 more source
Crystal structure of 3,6-bis (dimethylamino) acridine hydroperchloride (acridine orange・HClO4) [PDF]
, 1999 [Abstract] Single crystals of 3,6-bis(dimethylamino)acridine hydroperchloride (acridine orange・HClO4) was prepared and molecular structure was crystallographically determined.application/pdfdepartmental bulletin ...
マエカワ, マサヒコ +7 more
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