Results 11 to 20 of about 40,002 (209)

Acridine form IX [PDF]

Acta Crystallographica Section E: Crystallographic Communications, 2019
We report a new polymorph of acridine, C13H9N, denoted form IX, obtained as thin needles by slow evaporation of a toluene solution. The structure was solved and refined from powder X-ray data. The structures of five unsolvated forms were previously known,
Peter W. Stephens, Einat Schur, Saul H. Lapidus, Joel Bernstein   +3 more
doaj   +3 more sources

Acridine 0.75-hydrate [PDF]

Acta Crystallographica Section E, 2011
The title compound, C13H9N·0.75H2O was obtained during a study of the polymorphic system of acridine, by slow evaporation from an ethanol–water solution.
Andreas Lemmerer, Joel Bernstein, Einat Schur, Radion Vainer   +3 more
doaj   +3 more sources

Electron-Deficient Acetylenes as Three-Modal Adjuvants in S_N^H Reaction of Pyridinoids with Phosphorus Nucleophiles

Molecules, 2021
Publications covering a new easy metal-free functionalization of pyridinoids (pyridines, quinolines, isoquinolines, acridine) under the action of the system of electron-deficient acetylenes (acetylenecarboxylic acid esters, acylacetylenes)/P-nucleophiles
Boris A. Trofimov, Pavel A. Volkov, Anton A. Telezhkin   +2 more
doaj   +1 more source

Comparative Study Regarding the Properties of Methylene Blue and Proflavine and Their Optimal Concentrations for In Vitro and In Vivo Applications

Diagnostics, 2020
Methylene blue and proflavine are fluorescent dyes used to stain nucleic acid from the molecular level to the tissue level. Already clinically used for sentinel node mapping, detection of neuroendocrine tumors, methemoglobinemia, septic shock, ifosfamide-
Maria-Eliza Nedu, Mihaela Tertis, Cecilia Cristea, Alexandru Valentin Georgescu   +3 more
doaj   +1 more source

Acridine Based N-Acylhydrazone Derivatives as Potential Anticancer Agents: Synthesis, Characterization and ctDNA/HSA Spectroscopic Binding Properties

Molecules, 2022
A series of novel acridine N-acylhydrazone derivatives have been synthesized as potential topoisomerase I/II inhibitors, and their binding (calf thymus DNA—ctDNA and human serum albumin—HSA) and biological activities as potential anticancer agents on ...
Mária Vilková, Monika Hudáčová, Nikola Palušeková, Rastislav Jendželovský, Miroslav Almáši, Tibor Béres, Peter Fedoročko, Mária Kožurková   +7 more
doaj   +1 more source

Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives

Molecules, 2012
Several acridine derivatives were synthesized and their anti-proliferative activity was determined. The most active molecules were derivatives of 5-methylacridine-4-carboxylic acid. The DNA binding properties of the synthesized acridines were analyzed by
Ramon Eritja, Rubén Ferreira, Stefania Mazzini, Anna Aviñó   +3 more
doaj   +1 more source

Conjugation with Acridines Turns Nuclear Localization Sequence into Highly Active Antimicrobial Peptide

Engineering, 2015
The emergence of multidrug-resistant bacteria creates an urgent need for alternative antibiotics with new mechanisms of action. In this study, we synthesized a novel type of antimicrobial agent, Acr3-NLS, by conjugating hydrophobic acridines to the N ...
Wei Zhang, Xiaoli Yang, Jingjing Song, Xin Zheng, Jianbo Chen, Panpan Ma, Bangzhi Zhang, Rui Wang   +7 more
doaj   +1 more source

Crystal structure of 9-(3-bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione

Acta Crystallographica Section E, 2014
The title compound C25H29BrClNO4, comprises a 3,3,6,6-tetramethyltetrahydroacridine-1,8-dione ring system that carries a hydroxyethyl substituent on the acridine N atom and a 3-bromo-5-chloro-2-hydroxyphenyl ring on the central methine C atom of the ...
Antar A. Abdelhamid, Shaaban K. Mohamed, Jim Simpson   +2 more
doaj   +1 more source

The crystallography of acridine. III. The structure of acridine II [PDF]

Acta Crystallographica, 1960
A three-dimensional analysis of a second crystalline form of acridine is described.
Phillips, D.C., Ahmed, F.R., Barnes, W.H.   +2 more
openaire   +1 more source

Acridine as an Anti-Tumour Agent: A Critical Review

Molecules, 2022
This review summarized the current breakthroughs in the chemistry of acridines as anti-cancer agents, including new structural and biologically active acridine attributes.
Potlapati Varakumar, Kalirajan Rajagopal, Baliwada Aparna, Kannan Raman, Gowramma Byran, Clara Mariana Gonçalves Lima, Salma Rashid, Mohammed H. Nafady, Talha Bin Emran, Sławomir Wybraniec   +9 more
doaj   +1 more source