Results 11 to 20 of about 40,079 (224)

Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity

Pathogens, 2021
In the last few years, increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain unsatisfactory.
Iwona Gabriel, Kamila Rząd, Ewa Paluszkiewicz, Katarzyna Kozłowska-Tylingo   +3 more
doaj   +1 more source

Acridine as an Anti-Tumour Agent: A Critical Review

Molecules, 2022
This review summarized the current breakthroughs in the chemistry of acridines as anti-cancer agents, including new structural and biologically active acridine attributes.
Potlapati Varakumar, Kalirajan Rajagopal, Baliwada Aparna, Kannan Raman, Gowramma Byran, Clara Mariana Gonçalves Lima, Salma Rashid, Mohammed H. Nafady, Talha Bin Emran, Sławomir Wybraniec   +9 more
doaj   +1 more source

The crystallography of acridine. III. The structure of acridine II [PDF]

Acta Crystallographica, 1960
A three-dimensional analysis of a second crystalline form of acridine is described.
Phillips, D.C., Ahmed, F.R., Barnes, W.H.   +2 more
openaire   +1 more source

Utilizing a Spiro Core with Acridine- and Phenothiazine-Based New Hole Transporting Materials for Highly Efficient Green Phosphorescent Organic Light-Emitting Diodes

Molecules, 2018
Two new hole transporting materials, 2,7-bis(9,9-diphenylacridin-10(9H)-yl)-9,9′ spirobi[fluorene] (SP1) and 2,7-di(10H-phenothiazin-10-yl)-9,9′-spirobi[fluorene] (SP2), were designed and synthesized by using the Buchwald–Hartwig coupling reaction with a
Ramanaskanda Braveenth, Il-Ji Bae, Ji-Hun Han, Wu Qiong, Guk Seon, Kanthasamy Raagulan, Kihun Yang, Young Hee Park, Miyoung Kim, Kyu Yun Chai   +9 more
doaj   +1 more source

Comparative Study Regarding the Properties of Methylene Blue and Proflavine and Their Optimal Concentrations for In Vitro and In Vivo Applications

Diagnostics, 2020
Methylene blue and proflavine are fluorescent dyes used to stain nucleic acid from the molecular level to the tissue level. Already clinically used for sentinel node mapping, detection of neuroendocrine tumors, methemoglobinemia, septic shock, ifosfamide-
Maria-Eliza Nedu, Mihaela Tertis, Cecilia Cristea, Alexandru Valentin Georgescu   +3 more
doaj   +1 more source

Crystal Structure of a New 1:1 Acridine-Diclofenac Salt, Obtained with High Yield by a Mechanochemical Approach

Crystals, 2022
The liquid-assisted grinding (LAG) approach was exploited to efficiently produce a new salt cocrystal with a minimum expenditure of reagents and energy, with possible application in the pharmaceutical field.
Artur Mirocki, Eleonora Conterosito, Luca Palin, Artur Sikorski, Marco Milanesio, Mattia Lopresti   +5 more
doaj   +1 more source

Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives

Molecules, 2012
Several acridine derivatives were synthesized and their anti-proliferative activity was determined. The most active molecules were derivatives of 5-methylacridine-4-carboxylic acid. The DNA binding properties of the synthesized acridines were analyzed by
Ramon Eritja, Rubén Ferreira, Stefania Mazzini, Anna Aviñó   +3 more
doaj   +1 more source

Acridino-Diaza-20-Crown-6 Ethers: New Macrocyclic Hosts for Optochemical Metal Ion Sensing

Molecules, 2021
Acridino-diaza-20-crown-6 ether derivatives as new turn-on type fluorescent chemosensors with an excellent functionality and photophysical properties have been designed and synthesized for metal ion-selective optochemical sensing applications ...
Ádám Golcs, Korinna Kovács, Panna Vezse, Tünde Tóth, Péter Huszthy   +4 more
doaj   +1 more source

Conjugation with Acridines Turns Nuclear Localization Sequence into Highly Active Antimicrobial Peptide

Engineering, 2015
The emergence of multidrug-resistant bacteria creates an urgent need for alternative antibiotics with new mechanisms of action. In this study, we synthesized a novel type of antimicrobial agent, Acr3-NLS, by conjugating hydrophobic acridines to the N ...
Wei Zhang, Xiaoli Yang, Jingjing Song, Xin Zheng, Jianbo Chen, Panpan Ma, Bangzhi Zhang, Rui Wang   +7 more
doaj   +1 more source

Crystal structure of 9-(3-bromo-5-chloro-2-hydroxyphenyl)-10-(2-hydroxyethyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione

Acta Crystallographica Section E, 2014
The title compound C25H29BrClNO4, comprises a 3,3,6,6-tetramethyltetrahydroacridine-1,8-dione ring system that carries a hydroxyethyl substituent on the acridine N atom and a 3-bromo-5-chloro-2-hydroxyphenyl ring on the central methine C atom of the ...
Antar A. Abdelhamid, Shaaban K. Mohamed, Jim Simpson   +2 more
doaj   +1 more source