Results 11 to 20 of about 53,333 (203)

Supramolecular interactions in a 1:1 co-crystal of acridine and 3-chlorothiophene-2-carboxylic acid

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the title co-crystal, C5H3ClO2S·C13H9N, the components interact with each other via an O—H...N hydrogen bond. Acridine–acridine stacking, thiophene–thiophene stacking and acridine–thiophene C—H...π interactions also occur in the crystal.
Olakkandiyil Prajina, Packianathan Thomas Muthiah, Franc Perdih   +2 more
doaj   +2 more sources

Acridine–Isoxazole and Acridine–Azirine Hybrids: Synthesis, Photochemical Transformations in the UV/Visible Radiation Boundary Region, and Anticancer Activity

Molecules
Easy-to-handle N-hydroxyacridinecarbimidoyl chloride hydrochlorides were synthesized as convenient nitrile oxide precursors in the preparation of 3-(acridin-9/2-yl)isoxazole derivatives via 1,3-dipolar cycloaddition with terminal alkynes, 1,1 ...
Ekaterina E. Galenko, Mikhail S. Novikov, Alexander S. Bunev, Alexander F. Khlebnikov   +3 more
doaj   +2 more sources

2,6-Dimethylphenyl acridine-9-carboxylate

Acta Crystallographica Section E, 2013
In the title compound, C22H17NO2, the acridine ring system and the benzene ring are oriented at a dihedral angle of 37.7 (1)°. The carboxyl group is twisted at an angle of 67.7 (1)° relative to the acridine skeleton. In the crystal,
Damian Trzybiński, Michał Wera, Karol Krzymiński, Jerzy Błażejowski   +3 more
doaj   +2 more sources

A review of published data on acridine derivatives with different biological activities [PDF]

Kragujevac Journal of Science, 2018
Acridine ring can be found in molecules used in many different spheres, including industry and medicine. Nowadays, even acridines with antibacterial activity are of research interest due to increasing bacterial resistance.
Rupar Jelena S., Dobričić Vladimir D., Aleksić Mara M., Brborić Jasmina S., Čudina Olivera A.   +4 more
doaj   +5 more sources

Biological and Teratogenic Evaluations of Nitrogen Heterocycles for Anticancer Therapy [PDF]

Pharmaceuticals
Background: Heterocycle compounds with acridine, quinoline, indole, and pyridine nuclei are potentially active for anticancer activity since they can promote inhibition of vital enzymes, decreasing cell survival after binding to biomolecules.
Jéssica Celerino dos Santos, Josival Emanuel Ferreira Alves, Rafael David Souto de Azevedo, Josefa Gerlane da Silva, Maria Regina de Oliveira Silva, Lucia Patrícia Bezerra Gomes da Silva, Caio Victor Silva Soares, Jamire Muriel da Silva, Nabuêr Francieli da Silva, Jamerson Ferreira de Oliveira, Maria do Carmo Alves de Lima, Ricardo Olímpio de Moura, Sinara Mônica Vitalino de Almeida   +12 more
doaj   +2 more sources

Trypan Blue Exclusion Assay, Neutral Red, Acridine Orange and Propidium Iodide

, 2022
Cytotoxicity and cell viability assessments are very important parameters that are widely used in fundamental research and drug development to determine the safety profile of toxic compounds. These assays measure the degree to which a substance can cause
Kaiyven Afi-Leslie, Kelechi Okeke, Emmanuel Ogbodo, Arinzechukwu Ude   +3 more
core   +1 more source

Acridine form IX

Acta Crystallographica Section E: Crystallographic Communications, 2019
We report a new polymorph of acridine, C13H9N, denoted form IX, obtained as thin needles by slow evaporation of a toluene solution. The structure was solved and refined from powder X-ray data. The structures of five unsolvated forms were previously known,
Peter W. Stephens, Einat Schur, Saul H. Lapidus, Joel Bernstein   +3 more
doaj   +1 more source

Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives

Molecules, 2012
Several acridine derivatives were synthesized and their anti-proliferative activity was determined. The most active molecules were derivatives of 5-methylacridine-4-carboxylic acid. The DNA binding properties of the synthesized acridines were analyzed by
Ramon Eritja, Rubén Ferreira, Stefania Mazzini, Anna Aviñó   +3 more
doaj   +1 more source

Acridino-Diaza-20-Crown-6 Ethers: New Macrocyclic Hosts for Optochemical Metal Ion Sensing

Molecules, 2021
Acridino-diaza-20-crown-6 ether derivatives as new turn-on type fluorescent chemosensors with an excellent functionality and photophysical properties have been designed and synthesized for metal ion-selective optochemical sensing applications ...
Ádám Golcs, Korinna Kovács, Panna Vezse, Tünde Tóth, Péter Huszthy   +4 more
doaj   +1 more source

4,5-Bis(phthalimidomethyl)acridine [PDF]

, 2007
The structure of the title symmetrically disubstituted acridine derivative [systematic name: N, N'-(acridine-4,5-diyldimethylene) bisphthalimide], C31H19N3O4, has been determined at 120 K using synchrotron radiation.
Simpson, SJ, Fry FH, Tucker JHR, Tucker, James; id_orcid, Tapper, S, Simpson SJ, Fry, FH, Tapper S, Stephen J. Simpson, Fiona H. Fry, Sophia Tapper, James H. R. Tucker   +11 more
core   +1 more source