Results 281 to 290 of about 303,900 (388)

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

Advanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang, Jie Chen, Yunmiao Ma, Qingwei Zhou, Yu Kong, Yingxiang Chen, Junjie Chi, Haihua Hu   +7 more
wiley   +1 more source

Hydrogel-based devices for cancer diagnostics: a systematic review of materials and biomarkers. [PDF]

Future Sci OA
Saputri RI, Mensah A, Rodgers AM, Clark PG, Lowry D, Abuelhana A, Courtenay AJ.   +6 more
europepmc   +1 more source

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

Ultra‐Low‐Cost Hydrophobic Organic Coating for Highly Reversible Zinc Anodes

Angewandte Chemie, EarlyView.
A nanoscale hydrophobic 1,3‐Di(o‐tolyl)thiourea (DTH) layer (<14 nm) was deposited on zinc anodes for durable aqueous Zn‐ion batteries, costing merely 1.43×10−7 USD·Ah−1. By suppressing side reactions and dendrites, it achieved 2500‐cycle coin cells and a 143 Wh·kg−1 pouch cell (1200 cycles) with a record‐low additive cost (7.02×10−7 USD).
Shixun Wang, Zhiquan Wei, Yiqiao Wang, Shengnan Wang, Dedi Li, Hu Hong, Chuan Li, Yanbo Wang, Zhuoxi Wu, Shaoce Zhang, Xueying Zheng, Yi‐Chun Lu, Chunyi Zhi   +12 more
wiley   +2 more sources

Adhesive Photoinitiator Constructs Polymer Jackets on Enzymes: Direct, Release‐Free Cytosolic Delivery

Angewandte Chemie, EarlyView.
A supramolecular adhesive photoinitiator, GuCD⊃BP‐SH, overcomes a central dilemma in enzyme therapeutics. The initiator, featuring a guanidinium‐modified cyclodextrin (GuCD) host, triggers formation of a semi‐permeable polymer jacket directly on an enzyme.
Shuran He, Soumen Ghosh, Kou Okuro
wiley   +2 more sources

Effects of jujube and barberry extracts on the acrylamide formation in French fries in deep fryers and microwaves. [PDF]

Food Chem X
Gholampour F, Zeinali T, Ebadi Fathabad A, Yousefi S, Kamyar Z, Salmani F.   +5 more
europepmc   +1 more source

Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity

Angewandte Chemie, EarlyView.
A covalent allosteric inhibitor M029 was discovered for SHP1, a novel target for immunotherapy. M029 binds to a cryptic Cys remote from the active site, exhibits robust target engagement, and blocks tumor progression by stimulating antitumor immune response.
Zihan Qu, Frederick Nguele Meke, Zheng Zhang, Aaron D. Krabill, Christine S. Muli, Brenson A. Jassim, Jiajun Dong, Quyen D. Nguyen, Yunpeng Bai, Jinyue Li, Yiming Miao, Bardia Asadi, Levi M. Johnson, Jinmin Miao, Darci J. Trader, W. Andy Tao, Zhong‐Yin Zhang   +16 more
wiley   +2 more sources

Dietary Acrylamide Exposure and Its Correlation with Nutrition and Exercise Behaviours Among Turkish Adolescents. [PDF]

Nutrients
Metin Karaaslan M, Basaran B.
europepmc   +1 more source

Polyhydroxy structure orchestrates the intrinsic antibacterial property of acrylamide hydrogel as a versatile wound-healing dressing [PDF]

Lu Zhang, Yu-Jiao Tang, Wen-Qing Zhang, Jian Wang, Yu-Jian Cai, Tian-Yi Qin, Deteng Zhang, Zhao-Hui Wang, Ya-Long Wang   +8 more
openalex   +1 more source

Classical and New Approaches to Health Risk Assessment of Acrylamide Through the Consumption of Potato Chips. [PDF]

Food Sci Nutr
Afsari K, Kobarfard F, Yazdanpanah H, Docea AO, Tsitsimpikou C, Eslamizad S, Tsatsakis A.   +6 more
europepmc   +1 more source