Results 91 to 100 of about 4,216 (246)

Deep Eutectic Polymer Electrolyte with Competitive Hydrogen‐Bonding Coordination for High‐Voltage Nickel‐rich Lithium Metal Batteries

Advanced Science, EarlyView.
To stabilize high‐voltage Li||NCM811 batteries, we develop an in situ polymerized deep‐eutectic electrolyte (p‐DEPE) featuring competitive hydrogen‐bonding coordination. This design weakens Ni4+ adsorption, suppresses oxygen release, and enhances interfacial stability.
Yuxin Fan, Miao He, Yin Hu, Wei Chen, Yichao Yan, Tianyu Lei, Dongjiang Chen   +6 more
wiley   +1 more source

Sulfur-and selenium-targeting warheads: reaction-based design of electrophilic warheads for selective inhibition of enzyme

Frontiers in Chemistry
Covalent inhibitors for nucleophilic residues, particularly cysteine (Cys) and selenocysteine (Sec), have resurfaced as precision therapies for modifying disease-associated enzymes.
Neha Jain, Michio Iwaoka, Michio Iwaoka
doaj   +1 more source

Bridged h‐BN Nanosheets Coatings: Simultaneous Shielding Atomic‐Oxygen Irradiation and Achieving Superior Friction Performance

Advanced Science, EarlyView.
ABSTRACT To confront extreme space environments, a combination of inorganic and organic coatings can provide a pathway for offering highly durable radiation resistance and anti‐friction simultaneously. Herein, a strong interfacial 3D hydrogen‐bonding network is designed to create robust hexagonal boron nitride (h‐BN) based polymer coatings with ...
Zhuoyi Li, Changning Bai, Xingkai Zhang, Yusheng Liang, Wei Wu, Dingrui Zhou, Tao Du, Chunjin Wang   +7 more
wiley   +1 more source

Purification of vegetable oils from acrylamide pollutants using metal-organic frameworks

Scientific Reports
Acrylamide is a chemical compound that can form in certain foods during high-temperature cooking processes like frying, roasting, and baking. The presence of acrylamide in used cooking oil has environmental impact; therefore, the purification of used ...
Reda M. Abdelhameed, Randa S. Hasan, Hassan Abdel-Gawad   +2 more
doaj   +1 more source

Synthesis and Antioxidant Activities of Novel Pyrimidine Acrylamides as Inhibitors of Lipoxygenase: Molecular Modeling and In Silico Physicochemical Studies

Molecules
The pyrimidine ring is present in various biomolecules such as DNA and RNA bases, aminoacids, vitamins, etc. Additionally, many clinically used drugs including methotrexate and risperidone contain the pyrimidine heterocyclic scaffold as well.
Michail Saragatsis, Eleni Pontiki
doaj   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Real‐Time Stress Visualization of Hydrogels Enabled by Supramolecularly Switched Stretch‐Induced Phase Separation

Advanced Science, EarlyView.
Supramolecular hydrogels enable real‐time visualization of mechanical stress through supramolecular switching mechanotransduction. Adamantane‐modified cellulose functions as a responsive domain that undergoes an on–off transition between hydrated and dehydrated states via reversible β‐cyclodextrin–adamantane complexation and decomplexation.
Sooyeon Noh, Akihide Sugawara, Naoaki Ishihara, Takashi Konishi, Yuki Ueda, Ryuhei Motokawa, Yoshinori Takashima, Hiroshi Uyama   +7 more
wiley   +1 more source

Multi‐Stimuli Responsive Viologen‐Crosslinked Eutectogels Derived From Natural Deep Eutectic Solvents for Information Security and Motion Detection

Advanced Science, EarlyView.
Described herein is the development of an organic eutectic gel based on a deep eutectic mixture of naturally derived betaine and lactic acid. The eutectic gels exhibit reversible color‐switching in response to multiple stimuli including strain, UV light, and temperature, enabling advanced applications in information security, intelligent wearable ...
Zhiang Bai, Wai Lean Koay, Xin Yi Oh, Vinh Xuan Truong   +3 more
wiley   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

High‐Performance Transparent Solid Polymer Electrolyte Based on Copolymer of Deep Eutectic Electrolyte and Methyl Methacrylate for Electrochemical Devices

Advanced Science, EarlyView.
A copolymerization strategy using a polymerizable deep eutectic electrolyte with MMA forms efficient ion‐transport pathways while maintaining excellent transparency. The solid polymer electrolyte simultaneously achieves 17.8 MPa mechanical strength and 1.43 mS cm−1 ionic conductivity, enhancing long‐term cycling stability in Li|LFP batteries and ...
Tingting Chen, Sijia Han, Likun Wang, Sainan Ma, Liping Zhang, Yong Liu, Gaorong Han   +6 more
wiley   +1 more source