Results 51 to 60 of about 8,172 (292)
Bile Acid Sequestrants Based on Natural and Synthetic Gels
Gels, 2023 Bile acid sequestrants (BASs) are non-systemic therapeutic agents used for the management of hypercholesterolemia. They are generally safe and not associated with serious systemic adverse effects.
Magdalena-Cristina Stanciu +2 more
doaj +1 more source
Addition-substitution reactions of 2-thio-3-chloroacrylamides with carbon, nitrogen, oxygen, sulfur and selenium nucleophiles [PDF]
, 2011 Synthetically versatile conjugate addition of a range of carbon, nitrogen, oxygen, sulfur and selenium nucleophiles to the highly functionalised 2-thio-3-chloroacrylamides is described.
Chopra, Jay +7 more
core +1 more source
Determination of protein binding affinities within hydrogel-based molecularly imprinted polymers (HydroMIPs) [PDF]
, 2014 Hydrogel-based molecularly imprinted polymers (HydroMIPs) were prepared for several proteins (haemoglobin, myoglobin and catalase) using a family of acrylamide-based monomers.
Alexander +26 more
core +2 more sources
Copper mediated polymerization without external deoxygenation or oxygen scavengers [PDF]
, 2018 Overcoming the challenge of rigorous deoxygenation in copper mediated controlled radical polymerization processes (e.g. ATRP), we report a simple Cu(0)‐RDRP system in the absence of external additives (e.g. reducing agents, enzymes etc.).
Anastasaki, Athina +6 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Effect of Traditional Stir-Frying on the Characteristics and Quality of Mutton Sao Zi
Frontiers in Nutrition, 2022 The effects of stir-frying stage and time on the formation of Maillard reaction products (MRP) and potentially hazardous substances with time in stir-fried mutton sao zi were investigated.
Shuang Bai +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Anti-breast cancer activity of some novel quinoline derivatives
Acta Pharmaceutica, 2015 To discover new bioactive lead compounds for medicinal purposes, 2-cyano-3-(4-substituted)-N-(quinolin-3-yl) acrylamide derivatives 2–24, chromenes 25, 26 and benzochromenes 27, 28 were synthesized.
Ghorab Mostafa M., Alsaid Mansour S.
doaj +1 more source
Automated synthesis of monodisperse oligomers, featuring sequence control and tailored functionalization [PDF]
, 2016 Long, multifunctional sequence-defined oligomers were obtairred on solid support from a protecting-group-free two-step iterative protocol, based on the inherent reactivity of a readily available molecule containing an isocyanate and a thiolactone ...
Du Prez, Filip +4 more
core +4 more sources
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source