Results 31 to 40 of about 5,780 (194)

High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway[S]

open access: yesJournal of Lipid Research, 2013
Long-chain acyl-CoA synthetases (ACSL) play key roles in fatty acid metabolism in liver and other metabolic tissues in an isozyme-specific manner. In this study, we examined the effects of a fructose-enriched diet on expressions of ACSL isoforms in the ...
Bin Dong   +3 more
doaj   +1 more source

The Placentas of Women Who Suffer an Episode of Psychosis during Pregnancy Have Increased Lipid Peroxidation with Evidence of Ferroptosis

open access: yesBiomolecules, 2023
Psychosis is a complex entity characterized by psychological, behavioral, and motor alterations resulting in a loss of contact with reality. Although it is not common, pregnancy can be a period in which a first episode of psychosis can manifest ...
Miguel A. Ortega   +18 more
doaj   +1 more source

Endocrine remodelling of the adult intestine sustains reproduction in Drosophila. [PDF]

open access: yes, 2015
The production of offspring is energetically costly and relies on incompletely understood mechanisms that generate a positive energy balance. In mothers of many species, changes in key energy-associated internal organs are common yet poorly characterised
Abdou   +90 more
core   +2 more sources

Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption

open access: yesMolecular Metabolism, 2016
Objective: The family of acyl-CoA synthetase enzymes (ACSL) activates fatty acids within cells to generate long chain fatty acyl CoA (FACoA). The differing metabolic fates of FACoAs such as incorporation into neutral lipids, phospholipids, and oxidation ...
Thomas A. Bowman   +9 more
doaj   +1 more source

An Integrated Transcriptomics and Lipidomics Analysis Reveals That Ergosterol Is Required for Host Defense Against Bacterial Infection in Drosophila

open access: yesFrontiers in Immunology, 2022
Animals adjust their lipid metabolism states in response to pathogens infection. However, the underlying molecular mechanisms for how lipid metabolism responds to infection remain to be elusive.
Zihao Deng   +8 more
doaj   +1 more source

ESTUDO DE ISÓTOPOS ESTÁVEIS PARA CONFIRMAR INTERCONEXÕES ENTRE LAGOAS E ÁGUAS SUBTERRÂNEAS, SETE LAGOAS/MG

open access: yesRevista Águas Subterrâneas, 2019
O suprimento de água da cidade de Sete Lagoas/MG é quase totalmente subterrânea do Aquífero Cárstico Sete Lagoas (ACSL), com uma pequena contribuição de um aquífero fraturado.
PAULO HENRIQUE GALVÃO   +3 more
doaj   +1 more source

Bromelain effectively suppresses Kras-mutant colorectal cancer by stimulating ferroptosis

open access: yesAnimal Cells and Systems, 2018
Here, we investigated the possible anti-cancer properties of bromelain in Kras mutant human colorectal carcinoma cell lines and a mouse model harboring a Kras mutation.
Sujeong Park   +3 more
doaj   +1 more source

Molly reborn in C++ and R

open access: yesAnimal, 2020
The dairy cow model ‘Molly’ is a mixed discrete event-continuous system model that simulates feeding, metabolism and lactation of dairy cows. Decades of model development have resulted in a valuable tool in dairy science.
S.J.R. Woodward   +2 more
doaj   +1 more source

ACSL: Adaptive correlation-driven sparsity learning for deep neural network compression

open access: yesNeural Networks, 2021
Deep convolutional neural network compression has attracted lots of attention due to the need to deploy accurate models on resource-constrained edge devices. Existing techniques mostly focus on compressing networks for image-level classification, and it is not clear if they generalize well on network architectures for more challenging pixel-level tasks,
Wei He, Meiqing Wu, Siew-Kei Lam
openaire   +3 more sources

Regulation of Key Genes for Milk Fat Synthesis in Ruminants

open access: yesFrontiers in Nutrition, 2021
Milk fat is the most important and energy-rich substance in milk and plays an important role in the metabolism of nutrients during human growth and development. It is mainly used in the production of butter and yogurt.
Tong Mu   +5 more
doaj   +1 more source

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