Results 61 to 70 of about 5,780 (194)

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao   +10 more
wiley   +1 more source

Early Diagnosis and Severity Assessment of Weligama Coconut Leaf Wilt Disease and Coconut Caterpillar Infestation Using Deep Learning-Based Image Processing Techniques

open access: yesIEEE Access
Global Coconut (Cocos nucifera (L.)) cultivation faces significant challenges, including yield loss, due to pest and disease outbreaks. In particular, Weligama Coconut Leaf Wilt Disease (WCWLD) and Coconut Caterpillar Infestation (CCI) damage coconut ...
Samitha Vidhanaarachchi   +3 more
doaj   +1 more source

Effect of Non-Esterified Fatty Acids on Fatty Acid Metabolism-Related Genes in Calf Hepatocytes Cultured in Vitro

open access: yesCellular Physiology and Biochemistry, 2013
Background: NEFA plays numerous roles in the metabolism of glucose, lipids, and proteins. A number of experimental studies have shown that NEFA may have an important role in fatty acid metabolism in the liver, especially in dairy cows that experience ...
Peng Li   +10 more
doaj   +1 more source

Quantum Superposition of Massive Objects and Collapse Models

open access: yes, 2011
We analyze the requirements to test some of the most paradigmatic collapse models with a protocol that prepares quantum superpositions of massive objects.
C. W. Gardiner   +7 more
core   +1 more source

Macroscopic superpositions via nested interferometry: finite temperature and decoherence considerations [PDF]

open access: yes, 2012
Recently there has been much interest in optomechanical devices for the production of macroscopic quantum states. Here we focus on a proposed scheme for achieving macroscopic superpositions via nested interferometry.
Akram U   +12 more
core   +3 more sources

Prevalence of ACSL (rs6552828) polymorphism among runners

open access: yesActa Kinesiologiae Universitatis Tartuensis, 2019
The ACSL A/G polymorphism is associated with endurance trainability. Previous studies have demonstrated that homozygotes of the minor AA allele had a reduced maximal oxygen consumption response to training compared to the common GG allele homozygotes, and that the ACSL A/G single nucleotide polymorphism explained 6.1% of the variance in the VO2max ...
Alon Eliakim   +3 more
openaire   +2 more sources

Analysis of Microbial Community Structure and Functional Genes for Volatile Flavor in Stinky Tofu

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
This study integrated metagenomics to decipher the core microbiota (e.g., Pseudomonas, Acinetobacter, Enterobacter) and functional genes governing volatile flavor biosynthesis in stinky tofu. Key enzymes like glycoside hydrolases and alcohol dehydrogenases catalyzed carbohydrate and amino acid metabolism, generating characteristic compounds such as ...
Aiguo Luo   +4 more
wiley   +1 more source

Microbial and Metabolic Disorders in Cervical Cancer: Structural Insights, Biomarkers, Mechanisms, and Therapeutic Strategies

open access: yesCancer Science, Volume 116, Issue 12, Page 3228-3238, December 2025.
We unravel synergistic mechanisms by which microbial‐host metabolic networks regulate the tumor immune microenvironment and therapy resistance, bridging gaps between microbiota research and cancer metabolism. Identified biomarkers (e.g., Lactobacillus, C8‐ceramide‐1‐phosphate) and therapeutic approaches (e.g., FMT combined with immune checkpoint ...
Hong Tao   +6 more
wiley   +1 more source

Automated inference of ACSL function contracts using TriCera

open access: yes, 2021
This thesis explores synergies between deductive verification and model checking, by using the existing model checker TriCera to automatically infer specifications for the deductive verifier Frama-C. To accomplish this, a formal semantics is defined for a subset of ANSI C, extended with assume statements, called Csmall.
openaire   +2 more sources

A Configurable ACSL-Based Interface Generator for Simulated Systems

open access: yesSIMULATION, 1999
This paper presents a software tool for generat ing graphical interfaces for general-purpose ACSL simulation models. The tool is aimed to construct simulators for education and training in fields such as process control. Final users can manipulate the simulation from an upper level, avoiding the details of simulation, names of variables and ...
García Blanco, Miguel Ángel   +2 more
openaire   +2 more sources

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