Results 121 to 130 of about 2,979 (146)

PGC-1α regulates lipid accumulation by coordinating fatty acid synthesis and oxidation in goose fatty liver. [PDF]

Poult Sci
Li J, Lv M, Liu L, Geng T, Gong D, Zhao M.   +5 more
europepmc   +1 more source

Genomic Evaluation of the Genetic Structure and Analysis of Selective Evolutionary Signatures of Xupu Goose. [PDF]

Biology (Basel)
Zhu K, Ai Z, Cai Y, Li Y, Cheng Y, Zhang Y, Zhao W, Chen G.   +7 more
europepmc   +1 more source

Biochemistry and regulation of histone lysine L-lactylation. [PDF]

Nat Rev Mol Cell Biol
Sheng X, Lin H, Cole PA, Zhao Y.
europepmc   +1 more source

Cold-Induced Serum Short-Chain Fatty Acids Act as Markers of Brown Adipose Tissue Metabolism in Humans.

J Clin Endocrinol Metab
Monfort-Pires M, U-Din M, de Mello V, Saari T, Raiko J, Kerminen E, Rajander J, Hanhineva K, Fromme T, Landberg R, Klingenspor M, Virtanen KA.   +11 more
europepmc   +1 more source

Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy [PDF]

Molecular Cell, 2017
Overcoming metabolic stress is a critical step in tumor growth. Acetyl coenzyme A (acetyl-CoA) generated from glucose and acetate uptake is important for histone acetylation and gene expression. However, how acetyl-CoA is produced under nutritional stress is unclear.
Xinjian Li, Willie Yu, Xu Qian
exaly   +3 more sources

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ACSS2 boosts local histone acetylation

Nature Reviews Molecular Cell Biology, 2017
Eytan Zlotorynski, Zlotorynski Eytan
exaly   +2 more sources

Loss of ACSS2 expression predicts poor prognosis in patients with gastric cancer

Journal of Surgical Oncology, 2015
BackgroundRecent studies have demonstrated that acetyl‐CoA synthetase 2 (ACSS2) plays a critical role in cancer cell survival; however, the role of ACSS2 in gastric carcinogenesis has not been determined.MethodsWe investigated the expression of ACSS2 in human gastric cancer (GC) tissues using immunohistochemistry, and analyzed its clinicopathological ...
Hoon Hur, Young-Bae Kim, In-Hye Ham
exaly   +3 more sources

Possible involvement of ACSS2 gene in alcoholism

Journal of Neural Transmission, 2017
Alcoholism is a psychiatric disorder that composes one of the principal causes of health disabilities in the world population. Furthermore, the available pharmacotherapy is limited. Therefore, this research was carried out to better understand the basis of the underlying neurobiological processes of this disorder and to discover potential therapeutic ...
Andrea Frozino, Ribeiro, Roseli Boerngen, de Lacerda, Diego, Correia, Ana Lúcia, Brunialti-Godard, Débora Marques, de Miranda, Valdir Ribeiro, Campos, Valéria Fernandes, de Souza, Angela Maria, Ribeiro   +7 more
openaire   +2 more sources

Role of ACSS2-Ser267 phosphorylation in glioblastoma cells

2021
Glioblastoma (GBM) is the most common malignant brain cancer and preferentially generate acetyl-CoA from acetate as an alternative fuel source to promote biosynthesis and tumorigenesis. Acetate is converted into acetyl-CoA by the enzyme acetyl-CoA synthetase 2 (ACSS2).
Jing Ju, Jane Clifford
openaire   +1 more source

ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration

Proceedings of the National Academy of Sciences of the United States of America
Epigenetic mechanisms, including histone acetylation, regulate learning and memory and underlie Alzheimer’s disease and related dementia (ADRD). Acetyl-CoA synthetase 2 (ACSS2), an enzyme generating acetyl-CoA, locally regulates histone acetylation and gene expression in neuronal nuclei.
Kechun Yang, Virginia M -Y Lee, John A Dani   +2 more
exaly   +4 more sources