Results 1 to 10 of about 404,910 (338)
ACETYL-COA SYNTHETASE REGULATES HISTONE ACETYLATION AND HIPPOCAMPAL MEMORY [PDF]
Nature, 2017 Metabolic production of acetyl coenzyme A (acetyl-CoA) is linked to histone acetylation and gene regulation, but the precise mechanisms of this process are largely unknown.
Philipp Mews +5 more
semanticscholar +5 more sources
Definitions, 2020 Histone Acetylation involves covalent linkage of acetyl groups to highly basic histone proteins associated with DNA, particularly in active chromatin, and may be involved in regulation of gene expression.
semanticscholar +2 more sources
Cell Reports, 2019 SUMMARY Neuronal activity-inducible gene transcription correlates with rapid and transient increases in histone acetylation at promoters and enhancers of activity-regulated genes. Exactly how histone acetylation modulates transcription of these genes has
Liang-Fu Chen +12 more
semanticscholar +3 more sources
Transcription shapes genome-wide histone acetylation patterns
Nature Communications, 2021 Histone acetylation is a ubiquitous hallmark of transcription, but whether the link between histone acetylation and transcription is causal or consequential has not been addressed.
B. Martin +6 more
semanticscholar +2 more sources
Histone acetylation and the role of histone deacetylases in normal cyclic endometrium
Reproductive Biology and Endocrinology, 2020 Histone acetylation is a critical epigenetic modification that changes chromatin architecture and regulates gene expression by opening or closing the chromatin structure. It plays an essential role in cell cycle progression and differentiation. The human
Palak Gujral +3 more
semanticscholar +3 more sources
Cell Reports, 2019 SUMMARY The impact of glucose metabolism on muscle regeneration remains unresolved. We identify glucose metabolism as a crucial driver of histone acetylation and myogenic cell fate.
Nora Yucel +9 more
semanticscholar +3 more sources
Erasers of histone acetylation: the histone deacetylase enzymes. [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl functional groups from the lysine residues of both histone and nonhistone proteins. In humans, there are 18 HDAC enzymes that use either zinc- or NAD(+)-dependent mechanisms to deacetylate acetyl lysine substrates.
E. Seto, Minoru Yoshida
semanticscholar +3 more sources
Histone Acetylation Dynamics Integrates Metabolic Activity to Regulate Plant Response to Stress
Frontiers in Plant Science, 2019 Histone lysine acetylation is an essential chromatin modification for epigenetic regulation of gene expression during plant response to stress. On the other hand, enzymes involved in histone acetylation homeostasis require primary metabolites as ...
Yongfeng Hu +3 more
semanticscholar +3 more sources
Temporal and spatial distribution of histone acetylation in mouse molar development. [PDF]
PeerJHistone acetylation is one of the most widely studied histone modification, regulating a variety of biological activities like organ development and tumorigenesis. However, the role of histone acetylation in tooth development is poorly understood.
Du W, Luo W, Zheng L, Zhou X, Du W.
europepmc +3 more sources
Histone acetylation in neuronal (dys)function
Biomolecular Concepts, 2016 Cognitive functions require the expression of an appropriate pattern of genes in response to environmental stimuli. Over the last years, many studies have accumulated knowledge towards the understanding of molecular mechanisms that regulate neuronal gene
Emilie M. Bonnaud +2 more
semanticscholar +2 more sources