Results 61 to 70 of about 10,225,052 (294)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Grant Kajii and Polak (2000, Journal of Economic Theory) have identified weak decomposability as the key axiom to characterise the betweenness class for acts without the assumption of probabilistic sophistication, leaving, however, a small gap between necessary and sufficient conditions.
Roorda, Berend, Joosten, Reinoud A.M.G.
openaire +3 more sources
CONTEMPORARY INTERPRETATION ON TRANSPORT SECURITY IN RUSSIA AND IT ADMINISTRATIVE AND LEGAL REGULATION [PDF]
Krymskij Naučnyj Vestnik, 2015 Issues of technical development and regulation of security issues in the current international environment is now as important as ever for Russia. The problem of transport safety and standardization need a consistent interpretation for the purposes of ...
Fedor Vasiliev +2 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Affectio Societatis, 2010 This paper examines Freud´s and Lacan´s perspectives about suicide, emphasizing on the theoretical formulations and statutes given to it in the works of each of the authors mentioned.
David Vargas Castro.
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Human bombing - a religious act [PDF]
, 2014 The issue of human bombing, which is popularly known as suicide bombing has become important in the Western world since the 9/11 and 7/7 attacks. Since then the issue of human bombing has become important to academia, the media, and security experts ...
Ilyas, Mohammed
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Suboptimal Control of Asthma Among Diverse Patients: A US Mixed Methods Focus Group Study
Journal of Asthma and Allergy, 2022 Maureen George,1 Zaneta Balantac,2 Chris Gillette,3 Nabeel Farooqui,4 Tommi Tervonen,5 Caitlin Thomas,5 Ileen Gilbert,6 Hitesh Gandhi,6 Elliot Israel7 1School of Nursing, Columbia University, New York, NY, USA; 2Patient-Centered Research, Evidera, San ...
George M +8 more
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