Effects of hirudin-induced activation of nonenzymatic fibrinolysis during immobilization stress [PDF]
The specific inhibitor of thrombin, hirudin, was used for studying the mechanism of the activating effect of ACTH and adrenalin on nonenzymatic fibrinolytic activity (NEFA), the latter characterizing the function of the anticoagulation system (ACS ...
Baskova, I. P. +4 more
core +1 more source
The effect of therapeutic glucocorticoids on the adrenal response in a randomized controlled trial in patients with rheumatoid arthritis [PDF]
Objective. To measure the effect of low-dose systemic glucocorticoid treatment on the adrenal response to adrenocorticotropic hormone (ACTH) in patients with rheumatoid arthritis (RA). Methods.
Arnett +27 more
core +2 more sources
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
The effect of occupational responsibility and marital status on basal level of plasma ACTH in males [PDF]
life organs would be effected by different physiological pathways caused by stress.continuous stress could render the body vulnerable to various diseases.in this study the basal level of plasma ACTH was measured as probable indicator of stress in ...
S Sadeghi, M.T Shaebani rad
doaj
Role of ACTH receptor in adrenocortical tumor formation
Adrenocorticotrophin (ACTH) is the major regulatory hormone of steroid synthesis and secretion by adrenocortical cells. The actions of ACTH are mediated by its specific membrane receptor (ACTH-R).
A.C. Latronico
doaj +1 more source
The significance of ACTH for the process of formation of complex heparin compounds in the blood during immobilization stress [PDF]
Adrenocorticotropin (ACTH) was administered to rats at different times following adrenalectomy. Adrenocorticotropin caused a significant increase in the formation of heparin complexes even in the absence of stress factor.
Kudryashov, B. A. +3 more
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Influence of mirtazapine on salivary cortisol in depressed patients [PDF]
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C. +3 more
core +1 more source
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
ACTH, cortisol and IL-6 levels in athletes following magnesium supplementation [PDF]
Background: Physical exercise activates the hypothalamopituitary-adrenal (HPA) axis and induces the body's inflammatory response. Due to contemporary dietary habits and increased energy expenditure, athletes are susceptible to depletion of magnesium ions.
Dmitrašinović Gordana +5 more
doaj
Naloxone inhibits and morphine potentiates. The adrenal steroidogenic response to ACTH [PDF]
The adrenal actions were stereospecific since neither the positve stereoisomer of morphine, nor that of naloxone, had any effect on the adrenal response to exogenous adrenocorticotrophic hormone (ACTH).
Heybach, J. P., Vernikos, J.
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