Results 71 to 80 of about 129,829 (283)

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

The inflammatory process of gout and its treatment. [PDF]

, 2006
Gouty arthritis is a characteristically intense acute inflammatory reaction that erupts in response to articular deposits of monosodium urate (MSU) crystals.
Cronstein, Bruce N, Terkeltaub, Robert
core   +2 more sources

Prediction of treatment response in infantile epileptic spasms syndrome using EEG phase–amplitude coupling

Epilepsia Open, EarlyView.
Abstract Objective Treatment selection for infantile epileptic spasms syndrome (IESS) is complex and multifaceted, and currently no electroencephalogram (EEG) biomarkers can guide this decision by predicting treatment response. We tested the predictive value of phase–amplitude coupling (PAC) as IESS patients are known to have elevated PAC.
Soudeh Mostaghimi, Marco A. Pinto‐Orellana, Nathaniel Green, Daniel W. Shrey, Makoto Miyakoshi, Shaun A. Hussain, Beth A. Lopour   +6 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Physiological and behavioural aspects of housing stress in cattle [PDF]

, 2008
End of project reportThe effect of various space allowances on pituitary, adrenal, immune responses and performance was investigated in 72 Holstein x Friesian bulls.
Earley, Bernadette, Gupta, Sandeep, Murray, Margaret, Prendiville, Daniel J.   +3 more
core  

Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]

, 2014
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Ahima, ANDREIS, Arabi, Besedovsky, Blackwell, Bone, Bornstein, Carlson, Christopher D John, Clark, Connor, Costa, Csontos, Elenkov, Elmquist, GAILLARD, Heiman, Heuer, Hu, Huang, Jennifer A Parker, John, Julia C Buckingham, Kevin G Murphy, Kurt, Maffei, Mohn, Nishiyama, Ott, Pournajafi Nazarloo, Raber, Reyes, RIVIER, Rodr  guez-Wilhelmi, Saadia Basharat, Stephen R Bloom, Takao, Takemura, Vachharajani, Yousef, Zamorano   +40 more
core   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

The effect of MDMA on anterior pituitary hormones: a secondary analysis of a randomized placebo-controlled trial

Endocrine Connections
Background: 3,4-Methylenedioxymethamphetamine (MDMA), a psychoactive substance, has been proposed as a novel provocation test for oxytocin deficiency. Limited evidence suggests that MDMA may also stimulate the anterior pituitary. Therefore, this analysis
Cihan Atila, Sara-Jessica Camerin, Matthias E Liechti, Mirjam Christ-Crain   +3 more
doaj   +1 more source

Methodological considerations in the analysis of fecal glucocorticoid metabolites in tufted capuchins (Cebus apella) [PDF]

, 2013
Analysis of fecal glucocorticoid (GC) metabolites has recently become the standard method to monitor adrenocortical activity in primates noninvasively. However, given variation in the production, metabolism, and excretion of GCs across species and even ...
A Engelhardt, A Ganswindt, AC Brownie, BA Pettitt, Barbara Tiddi, BD Charlton, Brandon C. Wheeler, C Fichtel, C Touma, C Touma, CG Ohe von der, CP Groves, DJ Pappano, DM Fragaszy, E Addessi, E Möstl, E Möstl, Elisabetta Visalberghi, EV Wehncke, F Schwarzenberger, G Sabbatini, H Colby, J Caton, J Ostner, JC Beehner, JK Hodges, JL Brown, JM Keay, JP Higham, JW Lynch, JW Lynch Alfaro, K Milton, K Shutt, K Young, KE Hunt, M Carosi, M Heistermann, M Heistermann, M Heistermann, M Khan, M Pirovino, M Surbeck, Michael Heistermann, MJ Ulyan, MR Heintz, NI Bahr, PL Whitten, PL Whitten, R Martínez-Mota, R Palme, R Palme, R Palme, R Palme, RD Martin, RM Sapolsky, S Boinski, S Boinski, S Schatz, SF Anestis, SK Wasser, T Weingrill, TE Ziegler, U Kalbitzer, U Möhle, Urs Kalbitzer, W Goymann, WH Karasov   +66 more
core   +2 more sources

Exploring the Role of Dysregulated Arousal in the Relationship Between Trauma and Addictive Behaviors Among College Students

Journal of Counseling &Development, EarlyView.
ABSTRACT The relationship between trauma and addictive behaviors is well‐established, yet factors mediating this relationship remain understudied. Given the prevalence of addictive behaviors among collegiate populations, we used path analysis to explore the mediating role of arousal dysregulation in the relationship between childhood trauma and a ...
Amanda L. Giordano, Kate M. Dorrough, Deborah L. Smith, Peitao Zhu   +3 more
wiley   +1 more source