Both Season and Equid Type Affect Endogenous Adrenocorticotropic Hormone Concentrations in Healthy Donkeys, Mules and Hinnies in the United States. [PDF]
Goodrich EL +8 more
europepmc +1 more source
Time‐Restricted Feeding Alters Behavior in a Sex‐Specific Manner in Mice With Neuropathic Pain
Time‐restricted feeding (TRF) alleviates anxiety‐like behavior in male mice with neuropathic pain (NP), but not in females. Upon nerve injury, TRF altered the diurnal expression of transcripts in the hypothalamus. These findings suggest that TRF should be explored as a new therapeutic approach to alleviate the comorbid anxiety in NP.
Manqing Wen +3 more
wiley +1 more source
A rare case report of hepatoblastoma in a child with ectopic adrenocorticotropic hormone syndrome. [PDF]
Gao S +7 more
europepmc +1 more source
Role of Sleep Disturbances and Diabetes‐Related Distress on Glycemic Control: A Path Analysis
ABSTRACT Despite advancements in diabetes management technology, many patients with type 2 diabetes (T2D) struggle to achieve optimal glycemic control. Sleep disorders such as obstructive sleep apnea (OSA) and insomnia are common in T2D and linked to poor glycemic control. Insomnia, particularly with short sleep duration, may worsen glycemic control by
Bomin Jeon +2 more
wiley +1 more source
Case Report: Paradoxical responses to pasireotide in a patient with a silent corticotroph adenoma that transformed into an ACTH-secreting adenoma. [PDF]
Brona A +2 more
europepmc +1 more source
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte +3 more
wiley +1 more source
Cushing's disease and negative MRI: a single-center series, systematic literature review, and meta-analysis. [PDF]
Ghidoni F +27 more
europepmc +1 more source
PBMC transcriptomic profiling identifies FXYD7, SPSB2, SLC35E2A, C2, and SERPING1 as predictive biomarkers for irAEs in cancer patients receiving PD‐1/PD‐L1 blockade, enabling noninvasive risk stratification through liquid biopsy‐based classifiers with high accuracy. ABSTRACT Background Despite the remarkable success of immune checkpoint inhibitor (ICI)
Liting You +10 more
wiley +1 more source
Acid–Base Dysregulation Links Aging Metabolism to Frailty
Our Metabolic Buffer Model posits that chronic acid load from aging and accumulated stressors depletes total acid buffer reserve, disrupting intersystem crosstalk. This hidden homeostatic erosion drives clinical frailty and underlies homeostatic failure during stress, unifying Rockwood's deficit accumulation and Fried's phenotype models.
Wan‐Hui Liao +2 more
wiley +1 more source

