Results 231 to 240 of about 129,829 (283)

Defining a serum cortisol cutoff level post-CRH stimulation for diagnosing ACTH deficiency: A retrospective study validated by a nationwide registry. [PDF]

Front Endocrinol (Lausanne)
Izuchi T, Iwama S, Yamagami A, Kobayashi T, Suzuki K, Murase T, Ando M, Murasawa S, Mukai K, Takagi H, Fukuoka H, Handa T, Onoue T, Miyata T, Sugiyama M, Hagiwara D, Suga H, Banno R, Tahara S, Nishiyama M, Kageyama K, Otsuki M, Arima H.   +22 more
europepmc   +1 more source

AT1R in Central Nervous System Disorders: Unveiling Novel Mechanisms and Therapeutic Avenues for Addiction

Addiction Biology, Volume 31, Issue 4, April 2026.
AT1R signaling drives addiction through interconnected pathways, and AT1R antagonists target multiple nodes for therapeutic effects. ABSTRACT Although the angiotensin II type 1 receptor (AT1R), a pivotal component of the renin–angiotensin system (RAS), is associated with cardiovascular and renal homeostasis, burgeoning evidence implicates its critical ...
Jianan Lv, Dan Zhu, Sisi Song, Jiahui Zhou, Xiaoyu Zhang, Wenhua Zhou, Yu Liu, Zizhen Si   +7 more
wiley   +1 more source

Genetic background and management outcomes in primary bilateral macronodular adrenal hyperplasia: Implications for diagnosis and treatment-A retrospective cohort study. [PDF]

J Int Med Res
Gür EÖ, Karaıslı S, Çavdar Ü, Subaşıoğlu A, Eren Ö, Hacıyanlı SG, Pamuk BÖ, Ertürk MS, Hacıyanlı M.   +8 more
europepmc   +1 more source

Signal Amplification in the HPT Axis—Evidence for Its Existence, Location, Significance, and Molecular Mechanisms

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Development and validation of a machine learning model to predict prognostic outcomes in infantile epileptic spasms syndrome. [PDF]

Front Pediatr
Zuo C, Xue B, Mu X, Cao Z, Zhou H, Liu Z, Sun D.   +6 more
europepmc   +1 more source

Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome

Clinical Endocrinology, Volume 104, Issue 4, Page 302-311, April 2026.
ABSTRACT Objective Skeletal fragility is a common complication of endogenous Cushing's Syndrome (CS), although specific guidelines for managing bone health are lacking. This study aimed to assess clinicians' current engagement with bone health assessment and management in patients with endogenous CS. Design Retrospective‐cohort design. Patients Seventy‐
Preeshila Behary, Dinushan Raveendran, Ramesh Nair, Aimee Di Marco, Debbie Papadopoulou, Florian Wernig, Ali Abbara, Karim Meeran, Niamh Martin, Jeremy Cox, Alexander N. Comninos   +10 more
wiley   +1 more source

Resting neuroendocrine markers in relation to acute mental stress-induced adrenergic reactivity profiles in adults: The SABPA study. [PDF]

Physiol Rep
Naudé D, Smith W, von Känel R, Wentzel A.   +3 more
europepmc   +1 more source

Adrenocorticotropic hormone (ACTH).

Japanese Journal of Medicine, 1989
openaire   +4 more sources