Results 11 to 20 of about 794,065 (308)

Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium [PDF]

open access: yes, 2013
Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such
A Gnoni   +72 more
core   +11 more sources

The conserved Pelado/ZSWIM8 protein regulates actin dynamics by promoting linear actin filament polymerization

open access: yesLife Science Alliance, 2022
Pldo/ZSWIM8 is a conserved protein that promotes linear actin polymerization at the expense of branched actin in several contexts, ranging from Drosophila morphogenesis to human cell migration.
Claudia Molina-Pelayo   +3 more
doaj   +1 more source

MicroRNA-related cofilin abnormality in Alzheimer's disease. [PDF]

open access: yesPLoS ONE, 2010
Rod-like structures composed of actin and the actin-binding protein cofilin are found in Alzheimer's disease (AD) patients. However, the mechanisms underlying formation of these structures and their pathological consequences are still largely unknown. We
Jiaqi Yao   +5 more
doaj   +1 more source

Studies of functional properties of espin 1: Its interaction to actin filaments

open access: yesFrontiers in Cell and Developmental Biology, 2022
Actin is a multifunctional biomolecule that forms not only basic structural bodies such as filopodia and lamellipodia, but also large microvilli-like organelles like stereocilia.
Jeong Bin Yang   +4 more
doaj   +1 more source

Alpha-actinin of the chlorarchiniophyte Bigelowiella natans [PDF]

open access: yesPeerJ, 2018
The genome of the chlorarchiniophyte Bigelowiella natans codes for a protein annotated as an α-actinin-like protein. Analysis of the primary sequence indicate that this protein has the same domain structure as other α-actinins, a N-terminal actin-binding
Lars Backman
doaj   +2 more sources

A unique profilin-actin interface is important for malaria parasite motility. [PDF]

open access: yesPLoS Pathogens, 2017
Profilin is an actin monomer binding protein that provides ATP-actin for incorporation into actin filaments. In contrast to higher eukaryotic cells with their large filamentous actin structures, apicomplexan parasites typically contain only short and ...
Catherine A Moreau   +11 more
doaj   +1 more source

ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release. [PDF]

open access: yes, 2017
The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol.
Koehler, Carla M, Steffen, Janos
core   +1 more source

INTESTINAL ACTIN-LIKE PROTEIN

open access: yesThe Japanese Journal of Physiology, 1969
1) A preparation containing actin-like protein was extracted from the smooth muscle of the intestine with the use of STRAUB'S method.2) The viscometric observation suggested that intestinal actin-like proteinseemed to act as a monomer (globular actin) in salt-free solution and topolymerize to some polymer (fibrous actin) when low KCl was added.3) The ...
H, Yabu, R, Takahashi, E, Miyazaki
openaire   +3 more sources

F-actin-like filaments formed by plasmid segregation protein ParM [PDF]

open access: yesThe EMBO Journal, 2002
It was the general belief that DNA partitioning in prokaryotes is independent of a cytoskeletal structure, which in eukaryotic cells is indispensable for DNA segregation. Recently, however, immunofluorescence microscopy revealed highly dynamic, filamentous structures along the longitudinal axis of Escherichia coli formed by ParM, a plasmid-encoded ...
van den Ent, Fusinita   +4 more
openaire   +4 more sources

Control of lipid organization and actin assembly during clathrin-mediated endocytosis by the cytoplasmic tail of the rhomboid protein Rbd2. [PDF]

open access: yes, 2015
Clathrin-mediated endocytosis (CME) is facilitated by a precisely regulated burst of actin assembly. PtdIns(4,5)P2 is an important signaling lipid with conserved roles in CME and actin assembly regulation. Rhomboid family multipass transmembrane proteins
Cortesio, Christa L   +2 more
core   +1 more source

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