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Current Opinion in Cell Biology, 2005
Actin polymerization generates the force that deforms the cell membrane, pulls the cell forward and propels endosomes and bacteria within the cell. The mechanism of force generation has been probed using experimental biomimetic systems where force generation and movement occur by the same actin-polymerization processes observed in cells.
Cécile Sykes, Julie Plastino
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Actin polymerization generates the force that deforms the cell membrane, pulls the cell forward and propels endosomes and bacteria within the cell. The mechanism of force generation has been probed using experimental biomimetic systems where force generation and movement occur by the same actin-polymerization processes observed in cells.
Cécile Sykes, Julie Plastino
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, 1991 Almost 50 years ago actin was identified [Straub, 1942] in an extract of muscle tissue where — together with myosin — it forms the contractile protein-complex, actomyosin. Straub recognized that actin appears in two forms: In the absence of salt it can exist as a globular protein, G-actin, whereas on addition of traces of salt it changes into a highly ...
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Isolation of Actin and Actin-Binding Proteins
2016Actin-binding proteins mediate and regulate the dynamics of actin and the organization of highly ordered structures of F-actin. Villin is generally expressed in plant cells and is associated with G-actin or F-actin dependent on Ca2+ concentrations. Using a DNase I affinity column chromatography approach, the villin and the G-actin can be isolated from ...
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Annual Review of Medicine, 1990
Sun exposure has multiple well-documented acute and chronic effects of substantial medical importance. The most extensively studied of these are the effects on the skin. Acute effects include sunburn, phototoxic and photoallergic reactions, altered immunoreactivity, and a variety of photosensitivity disorders.
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Sun exposure has multiple well-documented acute and chronic effects of substantial medical importance. The most extensively studied of these are the effects on the skin. Acute effects include sunburn, phototoxic and photoallergic reactions, altered immunoreactivity, and a variety of photosensitivity disorders.
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Canadian Journal of Biochemistry and Cell Biology, 1985
Actin filaments can assemble at the barbed end and disassemble simultaneously at the pointed end. Prerequisites for this treadmilling reaction are the structural polarity of actin filaments and tight coupling of the actin assembly reaction and the adenosine triphosphate hydrolysis occurring during actin polymerization.
Albrecht Wegner +3 more
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Actin filaments can assemble at the barbed end and disassemble simultaneously at the pointed end. Prerequisites for this treadmilling reaction are the structural polarity of actin filaments and tight coupling of the actin assembly reaction and the adenosine triphosphate hydrolysis occurring during actin polymerization.
Albrecht Wegner +3 more
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Actin–microtubule crosstalk in cell biology
Nature reviews. Molecular cell biology, 2018M. Dogterom, G. Koenderink
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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
Nature Cell Biology, 2004E. Jacinto +6 more
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Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM
Nature Structural & Molecular Biology, 2018F. Merino +7 more
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