Results 201 to 210 of about 181,480 (263)

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

The kinetochore protein KNL-1 regulates the actin cytoskeleton to control dendrite branching. [PDF]

J Cell Biol
Alves Domingos H, Green M, Ouzounidis VR, Finlayson C, Prevo B, Cheerambathur DK.   +5 more
europepmc   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia. [PDF]

Front Neurol
López-Porras AI, Kruse AM, McClendon MT, Vélez-Ortega AC.   +3 more
europepmc   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

Sarcoglycans Role in Actin Cytoskeleton Dynamics and Cell Adhesion of Human Articular Chondrocytes: New Insights from siRNA-Mediated Gene Silencing. [PDF]

Int J Mol Sci
Centofanti A, Runci Anastasi M, Nicita F, Labellarte D, Scuruchi M, Pantano A, Freni J, Favaloro A, Vermiglio G.   +8 more
europepmc   +1 more source

Correction: Thiazole-fused androstenone and ethisterone derivatives: potent β- and γ-actin cytoskeleton inhibitors to treat melanoma tumors. [PDF]

RSC Med Chem
Adhikary S, Roy S, Budhathoki S, Chowdhury S, Stillwell A, Basnakian AG, Tackett A, Avaritt N, Milad M, Alam MA.   +9 more
europepmc   +1 more source

Active flows drive clustering and sorting of membrane components with differential affinity to dynamic actin cytoskeleton

Bhat A, Das A, Iyer M, Beri S, Talluri S, Koester D, Rao M, Mayor S.   +7 more
europepmc   +1 more source

Lipopolysaccharide-induced DNA damage response activates DNA-PKcs to drive actin cytoskeleton disruption and cardiac microvascular dysfunction in endotoxemia. [PDF]

Theranostics
Tan Y, Ouyang Y, Xiao L, Huang J, Li F, Ma Z, Tan C, Feng W, Davis E, Tang Y, Chang X, Li H.   +11 more
europepmc   +1 more source