Results 151 to 160 of about 6,799 (175)
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Characterization and expression of an actin-depolymerizing factor from Eimeria tenella
Parasitology Research, 2008Actin-depolymerizing factor (ADF) plays an important role in remodeling the actin cytoskeleton which contributes much to the invasion of host cells by the apicomplexan parasite. The gene encoding for Eimeria tenella ADF with one intron was cloned and identified by the E.
Jia-Hua, Xu +5 more
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Properties of purified actin depolymerizing factor from chick brain
Biochemistry, 1988Actin depolymerizing factor (ADF) from 19-day embryonic chick brains has been purified to greater than 98% homogeneity with a yield of 7.2 mg/100 g of brain. Quantitative immunoblotting with a monospecific antibody to ADF indicated that ADF comprises 0.3% of the total brain protein, resulting in an actual purification yield of about 20%.
K A, Giuliano +7 more
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NeuroReport, 1995
Hirano bodies are intracellular, paracrystalline, rod-like structures which contain actin, tropomyosin, vinculin, alpha-actinin, amyloid beta-protein precursor and several microtubule associated proteins (MAPs). These bodies are observed more frequently in the elderly and in a number of neurodegenerative diseases including Alzheimer's disease.
S K, Maciver, C R, Harrington
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Hirano bodies are intracellular, paracrystalline, rod-like structures which contain actin, tropomyosin, vinculin, alpha-actinin, amyloid beta-protein precursor and several microtubule associated proteins (MAPs). These bodies are observed more frequently in the elderly and in a number of neurodegenerative diseases including Alzheimer's disease.
S K, Maciver, C R, Harrington
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American Journal of Physiology-Renal Physiology, 1999
Apical membrane of renal proximal tubule cells is extremely sensitive to ischemia, with structural alterations occurring within 5 min. These changes are felt secondary to actin cytoskeletal disruption, yet the mechanism responsible is unknown. Actin depolymerizing factor (ADF), a 19-kDa actin-binding protein, has recently been shown to play an ...
N, Schwartz +6 more
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Apical membrane of renal proximal tubule cells is extremely sensitive to ischemia, with structural alterations occurring within 5 min. These changes are felt secondary to actin cytoskeletal disruption, yet the mechanism responsible is unknown. Actin depolymerizing factor (ADF), a 19-kDa actin-binding protein, has recently been shown to play an ...
N, Schwartz +6 more
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ELECTROPHORESIS, 2004
AbstractMembers of the actin‐depolymerizing factor (ADF)/cofilin family of proteins are expressed in all eukaryotic cells. In higher vertebrates, cells often express as many as three different ADF/cofilin genes and each of these proteins may be phosphorylated on serine 3, giving rise to up to six different species.
Alisa E, Shaw +5 more
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AbstractMembers of the actin‐depolymerizing factor (ADF)/cofilin family of proteins are expressed in all eukaryotic cells. In higher vertebrates, cells often express as many as three different ADF/cofilin genes and each of these proteins may be phosphorylated on serine 3, giving rise to up to six different species.
Alisa E, Shaw +5 more
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The Role of Actin Depolymerizing Factor in Regulating Actin Dynamics in Toxoplasma gondii
2010Apicomplexan parasites utilize a unique process of rapid motility termed gliding, which is coupled to their invasion of host cells. Gliding and invasion are dependent on parasite actin filaments, yet parasite actin is mostly non-filamentous. Filaments have been detected only transiently during gliding, suggesting that parasite actin filaments are ...
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ADF (Actin Depolymerizing Factor): The Breaker of the Polymer in Homeostasis
2019This chapter talks about the various isoforms of ADF that exist in different higher eukaryotes and its variation from apicomplexan ADF. We have discussed the structure, the function and the stability of the protein and the way it is regulated in different actin-mediated cellular processes to control the machinery of actin polymerization.
Samridhi Pathak +3 more
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Synthesis of actin-depolymerizing compounds
Bioorganic and Medicinal Chemistry Letters, 2009Kiyotake Suenaga +2 more
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