Results 1 to 10 of about 178 (148)
Research progress on the roles of actin-depolymerizing factor in plant stress responses
Frontiers in Plant Science, 2023 Actin-depolymerizing factors (ADFs) are highly conserved small-molecule actin-binding proteins found throughout eukaryotic cells. In land plants, ADFs form a small gene family that displays functional redundancy despite variations among its individual ...
Gong Yujie, Sun Yongwang, Wang Deying
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Plant actin depolymerizing factor: actin microfilament disassembly and more [PDF]
Journal of Plant Research, 2017 ACTIN DEPOLYMERIZING FACTOR (ADF) is a conserved protein among eukaryotes. The main function of ADF is the severing and depolymerizing filamentous actin (F-actin), thus regulating F-actin organization and dynamics and contributing to growth and development of the organisms.
Noriko Inada, Inada Noriko
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Frontiers in Immunology, 2022 The epidemic of avian coccidiosis seriously threatens the animals’ welfare and the economic gains of the poultry industry. Widespread in avian coccidiosis, Eimeria mitis (E.
Ruofeng Yan, Xiangrui Li, Mingmin Lu
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Frontiers in Plant Science, 2016 The actin cytoskeleton has been implicated in plant defense against pathogenic fungi, oomycetes and bacteria. Actin depolymerizing factors (ADF) are stimulus responsive actin cytoskeleton modulators.
Zhensheng Kang +2 more
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NMR solution structures of actin depolymerizing factor homology domains [PDF]
Protein Science, 2009 AbstractActin is one of the most conserved proteins in nature. Its assembly and disassembly are regulated by many proteins, including the family of actin‐depolymerizing factor homology (ADF‐H) domains. ADF‐H domains can be divided into five classes: ADF/cofilin, glia maturation factor (GMF), coactosin, twinfilin, and Abp1/drebrin.
Satoru Watanabe +2 more
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PLoS Biology, 2023 As the stimulus-responsive mediator of actin dynamics, actin-depolymerizing factor (ADF)/cofilin is subject to tight regulation. It is well known that kinase-mediated phosphorylation inactivates ADF/cofilin.
Qiannan Wang +6 more
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Computational Study of the Binding Mechanism of Actin-Depolymerizing Factor 1 with Actin in Arabidopsis thaliana. [PDF]
PLoS ONE, 2016 Actin is a highly conserved protein. It plays important roles in cellular function and exists either in the monomeric (G-actin) or polymeric form (F-actin).
Juan Du +4 more
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Isolation and characterization of a regulated form of actin depolymerizing factor [PDF]
The Journal of cell biology, 1993 Actin depolymerizing factor (ADF) is an 18.5-kD protein with pH-dependent reciprocal F-actin binding and severing/depolymerizing activities. We previously showed developing muscle down-regulates ADF (J. R. Bamburg and D. Bray. 1987. J. Cell Biol. 105: 2817-2825).
T E, Morgan +4 more
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eLife, 2021 Melanoma cells have been shown to undergo fast amoeboid (leader bleb-based) migration, requiring a single large bleb for migration. In leader blebs, is a rapid flow of cortical actin that drives the cell forward.
Maria F Ullo, Jeremy S Logue
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Actin filament remodeling by actin depolymerization factor/cofilin [PDF]
Proceedings of the National Academy of Sciences, 2010 We investigate, using molecular dynamics, how the severing protein, actin depolymerization factor (ADF)/cofilin, modulates the structure, conformational dynamics, and mechanical properties of actin filaments. The actin and cofilactin filament bending stiffness and corresponding persistence lengths obtained from all-atom simulations are comparable to ...
Jim, Pfaendtner +2 more
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