Microcystin-leucine arginine (MC-LR) is a potent tumor initiator that can induce malignant cell transformation. Cellular mechanical characteristics are pivotal parameters that are closely related to cell invasion.
Qiang Zhang +7 more
doaj +3 more sources
The Lipotubuloids of Ornithogalum umbellatum L. Contain Hyperstable Microtubules [PDF]
The epidermal cells of bracts, petals and sepals of Ornithogalum umbellatum L. (Star-of-Bethlehem, Asparagaceae) contain lipotubuloids, complex aggregates of lipid droplets (LDs) enmeshed by bundles of microtubules (MTs).
Krithika Yogeeswaran +4 more
doaj +2 more sources
The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo. [PDF]
Microtubule-microfilament interactions are important for cytokinesis and subcellular localization of proteins and mRNAs. In the early zebrafish embryo, astral microtubule-microfilament interactions also facilitate a stereotypic segregation pattern of ...
Sreelaja Nair +5 more
doaj +4 more sources
Suppression of Tumorigenicity in Breast Cancer Cells by the Microfilament Protein Profilin 1 [PDF]
Differential display screening was used to reveal differential gene expression between the tumorigenic breast cancer cell line CAL51 and nontumorigenic microcell hybrids obtained after transfer of human chromosome 17 into CAL51. The human profilin 1 (PFN1) gene was found overexpressed in the microcell hybrid clones compared with the parental line ...
K SchlÜter, S Scherneck, J JANKÉ
exaly +4 more sources
Research progress on the interaction mechanisms and functions between exosomes and the cytoskeleton [PDF]
Exosomes, as key mediators of intercellular communication, play a central regulatory role in cellular physiological and pathological processes through their dynamic interaction with the cytoskeleton.
Shili Yang +7 more
doaj +2 more sources
Genome-wide characterization and expression analysis of the ADF gene family in response to salt and drought stress in alfalfa (Medicago sativa) [PDF]
The microfilament cytoskeleton, formed by the process of actin polymerization, serves not only to support the morphology of the cell, but also to regulate a number of cellular activities.
Mengmeng Shi +12 more
doaj +2 more sources
Human skin fibroblasts (HSFs) approximate the multidirectional differentiation potential of mesenchymal stem cells, so they are often used in differentiation, cell cultures, and injury repair. They are an important seed source in the field of bone tissue
Xiaolan Huang +12 more
doaj +1 more source
Signaling via ITGB1/FAK and microfilament rearrangement mediates the internalization of Leptospira interrogans in mouse J774A.1 macrophages [PDF]
Leptospirosis caused by pathogenic Leptospira species is a worldwide zoonotic 2 infectious disease, but the mechanisms of leptospiral internalization remain poorly understood.
Zhao Xin +4 more
doaj +1 more source
BPAG1a and b associate with EB1 and EB3 and modulate vesicular transport, Golgi apparatus structure, and cell migration in C2.7 myoblasts. [PDF]
BPAG1a and BPAG1b (BPAG1a/b) constitute two major isoforms encoded by the dystonin (Dst) gene and show homology with MACF1a and MACF1b. These proteins are members of the plakin family, giant multi-modular proteins able to connect the intermediate ...
Kseniia Poliakova +6 more
doaj +1 more source
Involvement of the Actin Machinery in Programmed Cell Death
Programmed cell death (PCD) depicts a genetically encoded and an orderly mode of cellular mortality. When triggered by internal or external stimuli, cells initiate PCDs through evolutionary conserved regulatory mechanisms.
Weida Ren +3 more
doaj +1 more source

