Results 11 to 20 of about 16,394 (180)
International Journal of Oral Science, 2022 Microenvironmental biophysical factors play a fundamental role in controlling cell behaviors including cell morphology, proliferation, adhesion and differentiation, and even determining the cell fate.
Chenchen Zhou +5 more
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The Significant Role of the Microfilament System in Tumors
Frontiers in Oncology, 2021 Actin is the structural protein of microfilaments, and it usually exists in two forms: monomer and polymer. Among them, monomer actin is a spherical molecule composed of a polypeptide chain, also known as spherical actin.
Xin Jiang +6 more
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Villin: The major microfilament-associated protein of the intestinal microvillus [PDF]
Proceedings of the National Academy of Sciences, 1979 The major protein associated with actin in the microfilament core of intestinal microvilli has been purified. This protein, for which we propose the name villin, has a polypeptide molecular weight of approximately 95,000. Two arguments suggest that villin may be the microvillus crossfilament protein that links the microfilament core laterally down its ...
A, Bretscher, K, Weber
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
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Scientific Reports, 2023 mTOR complex 2 (mTORC2) has been implicated as a key regulator of glioblastoma cell migration. However, the roles of mTORC2 in the migrational control process have not been entirely elucidated.
Naphat Chantaravisoot +8 more
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Role of hypoxia in promoting migration and cell fusion of urine-derived stem cells
陆军军医大学学报, 2023 Objective To explore the effect of hypoxia on cell migration and fusion of urine-derived stem cells (USCs) in vitro, and observe the changes in cytoskeleton and cell polarity during the process.
ZHANG Nannan, HU Chaoqun, HE Yun
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Modulation of Microfilament Protein Composition by Transfected Cytoskeletal Actin Genes [PDF]
Molecular and Cellular Biology, 1988 HuT-14T is a highly tumorigenic fibroblast cell line which exhibits a reduced steady-state level of beta-actin due to coding mutations in one of two beta-actin alleles. The normal rate of total actin synthesis could be restored in some clones of cells following transfection of the functional beta-actin gene but not following transfection of the ...
S Y, Ng +4 more
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Dephosphorylated but not phosphorylated microtubule associated protein MAP1B binds to microfilaments [PDF]
FEBS Letters, 1996 We have reported that purified native MAP1B interacts with microtubules but not with microfilaments [Pedrotti and Islam, Cell Motil. Cytoskel. (1995) 30, 301–309]. However, MAP1B can be phosphorylated at multiple sites by casein kinase II (CKII) and proline‐directed protein kinases (PDPK) and immunoblotting studies show that purified native MAP1B is ...
Pedrotti, Barbara, Islam, Khalid
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Asian Journal of Andrology, 2016 Plastins are a family of actin binding proteins (ABPs) known to cross-link actin microfilaments in mammalian cells, creating actin microfilament bundles necessary to confer cell polarity and cell shape.
Nan Li, Chris KC Wong, C Yan Cheng
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LIM Kinases in Osteosarcoma Development
Cells, 2021 Tumorigenesis is a long-term and multistage process that often leads to the formation of metastases. During this pathological course, two major events appear to be crucial: primary tumour growth and metastatic expansion. In this context, despite research
Régis Brion +5 more
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