Results 61 to 70 of about 10,411 (204)

Design of B‐Cell Multi‐Epitope Subunit Vaccines Against Glaesserella parasuis by Reverse Vaccinology: An In Silico and In Vivo Study

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Yan Gong, Na Li, Ziheng Li, He Wang, Di Zhang, Hong Chu, Zhichao Lu, Aiqing Jia, Fengyang Li, Liancheng Lei, Zhong Peng   +10 more
wiley   +1 more source

Comparative Genomic Characterization of Actinobacillus pleuropneumoniae [PDF]

Journal of Bacteriology, 2010
ABSTRACT The Gram-negative bacterium Actinobacillus pleuropneumoniae is the etiologic agent of porcine contagious pleuropneumoniae, a lethal respiratory infectious disease causing great economic losses in the swine industry worldwide.
Zhuofei, Xu, Xiabing, Chen, Lu, Li, Tingting, Li, Shengyue, Wang, Huanchun, Chen, Rui, Zhou   +6 more
openaire   +2 more sources

Padronização do teste ELISA baseado em antígeno capsular purificado dos sorotipos 3, 5 e 7 de Actinobacillus pleuropneumoniae Standarization of ELISA test based on purified capsular antigen from serotypes 3, 5 and 7 of Actinobacillus pleuropneumoniae

Ciência Rural, 2000
Foram padronizados testes de ELISA (Enzyme-linked immunosorbent assay) baseados em antígeno capsular purificado de Actinobacillus pleuropneumoniae sorotipos 3, 5 e 7, prevalentes no Brasil.
Valéria Dutra, Itamar Piffer, Agueda Castagna de Vargas, Antônio Guidoni, Cátia Klein   +4 more
doaj   +1 more source

Concurrent host-pathogen gene expression in the lungs of pigs challenged with Actinobacillus pleuropneumoniae [PDF]

, 2015
BACKGROUND: Actinobacillus pleuropneumoniae causes pleuropneumonia in pigs, a disease which is associated with high morbidity and mortality, as well as impaired animal welfare.
Brogaard, Louise, Hansen, Mette Sif, Heegaard, Peter M. H., Jensen, Tim Kåre, Schou, Kirstine Klitgaard, Skovgaard, Kerstin   +5 more
core   +1 more source

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

PROTEOMICS, Volume 25, Issue 21-22, Page 160-176, November 2025.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic, Hamza Tahir, Nichollas E. Scott   +2 more
wiley   +1 more source

Evaluation of the Efficacy of a Vaccination Program against Actinobacillus pleuropneumoniae Based on Lung-Scoring at Slaughter

Animals, 2021
Porcine pleuropneumonia is of serious concern regarding lung health in pig production. Besides optimizing hygiene and pig management, specific vaccination against the causative agent, Actinobacillus pleuropneumoniae, is an important tool in the fight ...
Wolfgang Sipos, Vojislav Cvjetković, Branimir Dobrokes, Sabine Sipos   +3 more
doaj   +1 more source

Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes

Biotechnology and Applied Biochemistry, Volume 72, Issue 5, Page 1265-1273, October 2025.
ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo, Luz María Martínez, Noemí Flores, Georgina Hernández‐Chávez, Fernanda Cueto, Alfredo Martinez, Rosa Isela Corona‐González, Guillermo Gosset   +7 more
wiley   +1 more source

Expression levels of immune markers in infected pigs and their relation to breed and clinical symptoms [PDF]

, 2009
Background In pigs little is known about the role of innate immune defence in bacterial infections of the respiratory tract, despite their major role in pig production. In the present study we characterized and compared in vitro and in vivo activation of
Laurentiu Benga, Doris Hoeltig, Thomas Rehm, Hermann-Josef Rothkoetter, Reinhard Pabst, Peter Valentin-Weigand, FUGATO-consortium Iras   +6 more
core   +1 more source

Development of a Ready‐To‐Use Bioluminescence Immunosensor for the One‐Step Sensitive Detection of Antibodies Against African Swine Fever Virus

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
A ready‐to‐use bioluminescence immunosensor for rapid, one‐step detection of ASFV antibodies, offering high specificity, high sensitivity, and ease of use, with promising applications for point‐of‐care diagnostics. ABSTRACT Rapid and reliable analytical techniques play important roles in various research fields and are particularly crucial for ...
Zhonghui Zhang, Xuesai Li, Qingli Niu, Jinming Wang, Yanghe Liu, Dossêh Jean Apôtre Afayibo, Wenting Chen, Songlin Yang, Hong Yin, Guiquan Guan, Jifei Yang   +10 more
wiley   +1 more source

Evaluation of Transport Time on Stress Biomarkers in Pigs

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
The results of the study demonstrate that neither a transportation time of 1 h and 45 min (Group 1) nor a transportation time of 8 h (Group 2) has a negative impact on the animals. Serum cortisol was relatively unchanged, both between pre‐ and post‐transportation samples, as well as between groups. ABSTRACT Transportation of pigs may be associated with
Sarah Currie, M. Michael Swindle, Mark A. Suckow, Jerry Q. Zhang, Satish Adusumilli   +4 more
wiley   +1 more source