Results 41 to 50 of about 5,272 (178)

Actinobacillus pleuropneumoniae: The molecular determinants of virulence and pathogenesis

, 2021
Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is responsible for high economic losses in swine herds across the globe. Pleuropneumonia is characterized by severe respiratory distress and high mortality. The knowledge about the interaction between bacterium and host within the porcine respiratory tract has improved ...
Nahar, Nusrat, Turni, Conny, Tram, Greg, Blackall, Patrick J, Atack, John M   +4 more
openaire   +5 more sources

Extracellular Vesicles of Giardia duodenalis: Unravelling Their Virulence Factors and Potential to Induce Protection Against Experimental Giardiasis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo, Argüello‐García Raúl, Ortiz‐Lozano Dalia, Salazar‐Villatoro Lizbeth, Pech‐Santiago Edar Onam, Espinosa‐Cantellano Martha, Hernández‐Cueto Daniel, Silva‐Olivares D. Angélica, Betanzos Abigail, Ortega‐Pierres M. Guadalupe   +9 more
wiley   +1 more source

An Exploratory Study on the Pathogenic Role of Faecal Extracellular Vesicles in Metabolic Dysfunction‐Associated Steatotic Liver Disease Progression and in Drug‐Induced Liver Injury

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
Fecal extracellular vesicles (fEVs) from DILI patients have a distinct bacterial profile. This study provides evidence that bacterial EVs enter the bloodstream. DILI and MASLD F≥3 fEVs increase the pro‐inflammatory response and hepatocyte steatosis. FEVs from DILI patients enhance the hepatotoxic potential of diclofenac.
Antonio J. Ruiz‐Malagón, Marina Herraiz‐Vilela, Jose Pinazo‐Bandera, Juan Pedro Toro‐Ortiz, Carlos López‐Gómez, Ailec Ho‐Plagaro, Lourdes Garrido‐Sánchez, Mercedes Robles‐Díaz, Bernard Taminiau, Georges Daube, Judith Sanabria‐Cabrera, Gonzalo Matilla‐Cabello, Maria Isabel Lucena, Raúl J. Andrade, Eduardo García‐Fuentes, Miren García‐Cortes, Cristina Rodriguez‐Diaz   +16 more
wiley   +1 more source

Beyond nocardioform: Transcriptionally active microbes and host responses in equine mucoid placentitis

Equine Veterinary Journal, Volume 58, Issue 2, Page 601-618, March 2026.
Abstract Background Nocardioform placentitis (NP) is an understudied form of equine placentitis historically attributed to nocardioform bacteria, yet it remains uncertain whether these organisms are the sole pathogens involved. Objectives To elucidate the pathophysiology of NP and the host–pathogen interaction. Study Design In vivo clinical multi‐omics
Machteld van Heule, Margo Verstraete, Jamie Kaj Norris, Kinga Barbara Graniczkowsa, Kirsten E. Scoggin, Hossam El‐Sheikh Ali, Barry A. Ball, Ward De Spiegelaere, Peter Daels, Bart C. Weimer, Pouya Dini   +10 more
wiley   +1 more source

Padronização do teste ELISA baseado em antígeno capsular purificado dos sorotipos 3, 5 e 7 de Actinobacillus pleuropneumoniae Standarization of ELISA test based on purified capsular antigen from serotypes 3, 5 and 7 of Actinobacillus pleuropneumoniae

Ciência Rural, 2000
Foram padronizados testes de ELISA (Enzyme-linked immunosorbent assay) baseados em antígeno capsular purificado de Actinobacillus pleuropneumoniae sorotipos 3, 5 e 7, prevalentes no Brasil.
Valéria Dutra, Itamar Piffer, Agueda Castagna de Vargas, Antônio Guidoni, Cátia Klein   +4 more
doaj   +1 more source

A CRISPR/Cas12a-assisted rapid detection platform by biosensing the apxIVA of Actinobacillus pleuropneumoniae

Frontiers in Microbiology, 2022
Actinobacillus pleuropneumoniae is an important respiratory pig pathogen that causes substantial losses in the worldwide swine industry. Chronic or subclinical infection with no apparent clinical symptoms poses a challenge for preventing transmission ...
Tian Luan, Lu Wang, Jiyu Zhao, Hui Luan, Yueling Zhang, Chunlai Wang, Paul R. Langford, Siguo Liu, Wanjiang Zhang, Gang Li   +9 more
doaj   +1 more source

Mechanistic Landscape and Farm to Fork Control Strategies for Streptococcus suis: An Emerging Foodborne Threat

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Streptococcus suis (S. suis) is an emerging zoonotic agent that now rivals classical food‐borne pathogens in its global clinical burden of meningitis and septic shock. Recent epidemiological syntheses covering more than 30 countries now list over 1600 laboratory‐confirmed human cases with a pooled case‐fatality of about 12%, climbing beyond 18% in East
Wangyuan Yao, Meili Chen, Hongkai Ren, Qingqing Luo, Xuyuan Wang, Md. Akhtar, Zeeshan Ahmad Bhutta, Lianci Peng, Muhammad Yasir Nawaz, Mohammad Mehedi Hasan, Md. F. Kulyar, Rendong Fang, Zhong Peng   +12 more
wiley   +1 more source

Isolation and Characterization of a Highly Virulent Getah Virus Causing Acute Lethal Infection in Neonatal Piglets

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Getah virus (GETV) is a mosquito‐borne alphavirus with an expanding host range and an increasing impact on swine production, particularly in neonatal piglets. In this study, a severe disease outbreak characterized by acute diarrhea and high mortality occurred among suckling piglets on a commercial pig farm in central China.
Zhengxin Yang, Weidong Yan, Xuefei Wang, Mengjia Zhang, Zongyang Peng, Mengdi Zhang, Ahmed H. Ghonaim, Xuexiang Yu, Thi Trang Vy, Xugang Ku, Mingguang Zhou, Gaoyuan Xu, Anan Jongkaewwattana, Qigai He, Wentao Li, Shao-Lun Zhai   +15 more
wiley   +1 more source

Development of Magnetic Particle–Based Chemiluminescence Immunoassays for Detecting PCV2 VLP‐ and Rep‐Specific Antibodies and Their Combined Use for Immune Evaluation and Replication‐Associated Exposure Assessment

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine circovirus 2 (PCV2) remains a major swine pathogen, and interpretation of capsid protein (Cap)–based serology is challenging in vaccinated populations because vaccine‐induced Cap antibodies overlap with replication‐associated serological signals.
Mingxi Gou, Xiaoqing Song, Jie Fan, Zhixiong Chen, Zihao Kuang, Mengyao Lu, Zhongxin Fan, Meng Ge, Zhong Peng   +8 more
wiley   +1 more source

Microarray-based comparative genomic profiling of reference strains and selected Canadian field isolates of Actinobacillus pleuropneumoniae

BMC Genomics, 2009
Background Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is a highly contagious respiratory pathogen that causes severe losses to the swine industry worldwide.
MacInnes Janet I, Foote Simon J, Bouevitch Anne, Deslandes Vincent, Findlay Wendy A, Gouré Julien, Coulton James W, Nash John HE, Jacques Mario   +8 more
doaj   +1 more source