Results 61 to 70 of about 12,733 (270)

Beyond nocardioform: Transcriptionally active microbes and host responses in equine mucoid placentitis

Equine Veterinary Journal, Volume 58, Issue 2, Page 601-618, March 2026.
Abstract Background Nocardioform placentitis (NP) is an understudied form of equine placentitis historically attributed to nocardioform bacteria, yet it remains uncertain whether these organisms are the sole pathogens involved. Objectives To elucidate the pathophysiology of NP and the host–pathogen interaction. Study Design In vivo clinical multi‐omics
Machteld van Heule, Margo Verstraete, Jamie Kaj Norris, Kinga Barbara Graniczkowsa, Kirsten E. Scoggin, Hossam El‐Sheikh Ali, Barry A. Ball, Ward De Spiegelaere, Peter Daels, Bart C. Weimer, Pouya Dini   +10 more
wiley   +1 more source

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

Actinobacillus pleuropneumoniae: The molecular determinants of virulence and pathogenesis

, 2021
Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is responsible for high economic losses in swine herds across the globe. Pleuropneumonia is characterized by severe respiratory distress and high mortality. The knowledge about the interaction between bacterium and host within the porcine respiratory tract has improved ...
Nahar, Nusrat, Turni, Conny, Tram, Greg, Blackall, Patrick J, Atack, John M   +4 more
openaire   +4 more sources

Design of B‐Cell Multi‐Epitope Subunit Vaccines Against Glaesserella parasuis by Reverse Vaccinology: An In Silico and In Vivo Study

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Yan Gong, Na Li, Ziheng Li, He Wang, Di Zhang, Hong Chu, Zhichao Lu, Aiqing Jia, Fengyang Li, Liancheng Lei, Zhong Peng   +10 more
wiley   +1 more source

A CRISPR/Cas12a-assisted rapid detection platform by biosensing the apxIVA of Actinobacillus pleuropneumoniae

Frontiers in Microbiology, 2022
Actinobacillus pleuropneumoniae is an important respiratory pig pathogen that causes substantial losses in the worldwide swine industry. Chronic or subclinical infection with no apparent clinical symptoms poses a challenge for preventing transmission ...
Tian Luan, Lu Wang, Jiyu Zhao, Hui Luan, Yueling Zhang, Chunlai Wang, Paul R. Langford, Siguo Liu, Wanjiang Zhang, Gang Li   +9 more
doaj   +1 more source

Transposon mutagenesis in Actinobacillus pleuropneumoniae with a Tn10 derivative [PDF]

Journal of Bacteriology, 1993
A transposon mutagenesis procedure functional in the gram-negative swine pathogen Actinobacillus pleuropneumoniae was developed for the first time. The technique involved the use of a suicide conjugative plasmid, pLOF/Km, carrying a mini-Tn10 with an isopropyl-beta-D-thiogalactopyranoside (IPTG)-inducible transposase located outside the mobile element (
Tascón , Ruben-Ivan, Rodriguez-Ferri, Elias Fernando, Gutierrez-Martin, Cesar B, Rodriguez-Barbosa, Ignacio, Berche, Patrick, Vazquez-Boland, Jose A   +5 more
openaire   +3 more sources

A RNase H2‐Linked TaqMan‐MGB Quantitative Real‐Time PCR Assay for Differential Detection of Mycoplasma hyopneumoniae Live‐Attenuated Vaccine Strains

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Mycoplasma hyopneumoniae (M. hyopneumoniae), the etiological agent of porcine enzootic pneumonia, is one of the most prevalent and economically significant respiratory pathogens in the swine industry. Vaccination constitutes a primary strategy for controlling M. hyopneumoniae infections.
Kangyao Peng, Yanna Wei, Yuzi Wu, Ting Yuan, Jiahao Li, Ping Jiang, Qingyun Xie, Zhixin Feng, Anusak Kerdsin   +8 more
wiley   +1 more source

Padronização do teste ELISA baseado em antígeno capsular purificado dos sorotipos 3, 5 e 7 de Actinobacillus pleuropneumoniae Standarization of ELISA test based on purified capsular antigen from serotypes 3, 5 and 7 of Actinobacillus pleuropneumoniae

Ciência Rural, 2000
Foram padronizados testes de ELISA (Enzyme-linked immunosorbent assay) baseados em antígeno capsular purificado de Actinobacillus pleuropneumoniae sorotipos 3, 5 e 7, prevalentes no Brasil.
Valéria Dutra, Itamar Piffer, Agueda Castagna de Vargas, Antônio Guidoni, Cátia Klein   +4 more
doaj   +1 more source

A computational strategy for the search of regulatory small RNAs in Actinobacillus pleuropneumoniae. [PDF]

, 2016
Bacterial regulatory small RNAs (sRNAs) play important roles in gene regulation and are frequently connected to the expression of virulence factors in diverse bacteria.
Bazzolli, DMS, Bossé, JT, Gould, KA, Langford, PR, Li, Y, Rossi, CC, Witney, AA   +6 more
core   +2 more sources

Lipopolysaccharides of Actinobacillus pleuropneumoniae bind pig hemoglobin [PDF]

Infection and Immunity, 1995
A previous study indicated that lipopolysaccharides (LPS) extracted from Actinobacillus pleuropneumoniae bind two low-molecular-mass proteins, of approximately 10 and 11 kDa, present in porcine respiratory tract secretions (M. Bélanger, D. Dubreuil, and M. Jacques, Infect. Immun. 62:868-873, 1994).
M, Bélanger, C, Bégin, M, Jacques
openaire   +2 more sources