Journal of Veterinary Pharmacology and Therapeutics, Volume 48, Issue 4, Page 300-317, July 2025.ABSTRACT This meta‐analysis provides a population model of doxycycline (DOXY) disposition in pigs for computation of PK/PD cutoff values corresponding to differing modalities of DOXY administration orally in pigs. This analysis enables establishment of specific clinical breakpoints for the development of antimicrobial susceptibility testing of DOXY in ...
Pierre‐Louis Toutain +8 more
wiley +1 more source
Profiling microRNAs in lung tissue from pigs infected with Actinobacillus pleuropneumoniae [PDF]
, 2012 Background MicroRNAs (miRNAs) are a class of non-protein-coding genes that play a crucial regulatory role in mammalian development and disease. Whereas a large number of miRNAs have been annotated at the structural level during the latest years ...
Anthon, Christian +8 more
core +3 more sources
Presence and Seroprevalence of Actinobacillus pleuropneumoniae in Pigs in Turkey [PDF]
Acta Veterinaria Brno, 2007 In this study, the presence and seroprevalence of Actinobacillus pleuropneumoniae in pigs raised in various regions of Turkey were investigated. For this purpose, 384 lung, tonsil and blood samples were taken by random sampling during the slaughter. The pigs did not show any signs of clinical
Metiner, Kemal, Ak, Seyyal
openaire +2 more sources
Bacterial Outer Membrane Vesicles: From Physics to Clinical
MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou +7 more
wiley +1 more source
Efficacy in Reduction of Lung Lesions of a Toxin Expressing Whole-cell Vaccine Against Multiple Serovars of Actinobacillus Pleuropneumoniae in Growing Pigs [PDF]
, 2021 Preben Mortensen +5 more
openalex +1 more source
Expansion of the diversity of dispersin scaffolds
Acta Crystallographica Section D, Volume 81, Issue 3, Page 130-146, March 2025.Five GH20‐family dispersins were characterized for activity on aryl glycosides and poly‐β‐1,6‐linked N‐acetyl‐d‐glucosamine oligomers and three crystal structures were solved, including two complexes with bound inhibitors.Microorganisms are known to secrete copious amounts of extracellular polymeric substances (EPS) that form complex matrices around ...
Alexandra Males +20 more
wiley +1 more source
Whole‐Genomic Characterization of Two Different PRRSV‐1 Strains Isolated From a Single Pig
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Recent studies have demonstrated that porcine reproductive and respiratory syndrome virus 1 (PRRSV‐1) strains isolated from different farms in China have significant genomic heterogeneity, whereas strains from the same farm present a high degree of genomic similarity.
Bangjun Gong +23 more
wiley +1 more source
An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein [PDF]
, 2005 Campylobacter jejuni is a Gram-negative food-borne pathogen associated with gastroenteritis in humans as well as cases of the autoimmune disease Guillain Barre syndrome. C.
Altekruse +61 more
core +1 more source
The dose regimen formulation of doxycycline hydrochloride and florfenicol injection based on ex vivo pharmacokinetic-pharmacodynamic modeling against the Actinobacillus pleuropneumoniae in pigs [PDF]
, 2023 Yuanyuan Yuan +8 more
openalex +1 more source
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Enzootic pneumonia (EP) caused by Mycoplasma hyopneumoniae (M. hyopneumoniae) has a significant impact on swine production. Subtherapeutic exposures of tylvalosin in swine, often due to inconsistent dosing in feed or water, promote antimicrobial resistance.
Leonardo Teófilo Toledo +8 more
wiley +1 more source