Results 91 to 100 of about 120,144 (290)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Microarray analysis and barcoded pyrosequencing provide consistent microbial profiles depending on the source of human intestinal samples [PDF]

open access: yes, 2011
Large-scale and in-depth characterization of the intestinal microbiota necessitates application of high-throughput 16S rRNA gene-based technologies, such as barcoded pyrosequencing and phylogenetic microarray analysis.
Bogert, B., van den   +3 more
core   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

open access: yesFood Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao   +8 more
wiley   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

open access: yesFood Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu   +8 more
wiley   +1 more source

The oral microbiome of denture wearers is influenced by natural dentition [PDF]

open access: yes, 2015
Objectives: The composition of dental plaque has been well defined, whereas currently there is limited understanding of the composition of denture plaque and how it directly influences denture related stomatitis (DS).
Bradshaw, David   +13 more
core   +5 more sources

Penicillin-binding proteins in Actinobacteria [PDF]

open access: yesThe Journal of Antibiotics, 2014
Because some Actinobacteria, especially Streptomyces species, are β-lactam-producing bacteria, they have to have some self-resistant mechanism. The β-lactam biosynthetic gene clusters include genes for β-lactamases and penicillin-binding proteins (PBPs), suggesting that these are involved in self-resistance. However, direct evidence for the involvement
openaire   +2 more sources

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Characteristics of intestinal microbiota of infants according to data of sequencing of the 16s RRNA gene

open access: yesЖурнал инфектологии, 2017
The article presents the results of a single study the intestinal microbiota of healthy infants. Study was performed 11 fecal samples, followed by targeted sequencing the amplified sites on the 16S rRNA gene Miseq platform (Illumina, USA), according to ...
N. V. Gonchar   +3 more
doaj   +1 more source

Isolation and identification of bacterial endosymbionts in the brooding brittle star Amphipholis squamata [PDF]

open access: yes, 2016
Symbiotic associations with subcuticular bacteria (SCB) have been identified and studied in numerous echinoderms, including the SCB of the brooding brittle star, Amphipholis squamata.
Tedford, Abbey Rose
core   +1 more source

Characterization of wild and captive baboon gut microbiota and their antibiotic resistomes [PDF]

open access: yes, 2018
Antibiotic exposure results in acute and persistent shifts in the composition and function of microbial communities associated with vertebrate hosts.
Boolchandani, Manish   +9 more
core   +2 more sources

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