The protein kinase DYRK1B is a p53 target gene and functions as a negative feedback regulator of the transcription factor RFX7. [PDF]
Wilms G +8 more
europepmc +1 more source
METTL3/YTHDF1‐Driven SURF6 Promotes Prostate Cancer Stemness via CDK4
ABSTRACT Prostate cancer (PCa) remains a major health challenge globally, necessitating the identification of novel therapeutic targets to improve patient outcomes. This study investigates the role of the SURF6 gene in PCa, focusing on its expression patterns, molecular mechanisms, and biological behaviours in vitro and in vivo.
Yue Cheng +3 more
wiley +1 more source
Investigation of antimicrobial synergism of actinomycin derivatives from <i>Streptomyces parvus</i> 35M1 against <i>Escherichia coli</i> ATCC 25922. [PDF]
Can Ö +4 more
europepmc +1 more source
ABSTRACT Primary mediastinal lymphoma is rare in dogs and literature exploring this disease is limited. Therefore, the aim of this study was to describe presentation, treatment and outcome in a large cohort of dogs with mediastinal lymphoma and explore prognostic factors including chemotherapy protocol. This retrospective multi‐institute study included
Diogo Machado +11 more
wiley +1 more source
Gestational Trophoblastic Neoplasia Following Hydatidiform Mole and Non-Molar Pregnancy: Clinical and Prognostic Features from a 40-Year Cohort Study at a Reference Center in Southern Brazil. [PDF]
Uberti EMH +8 more
europepmc +1 more source
Development of a Machine Learning‑Based Prognostic Model for Intermediate Trophoblastic Tumors: A Single-Center Study With Web-Based Tool Implementation. [PDF]
Wang W +14 more
europepmc +1 more source
The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity. [PDF]
Będzińska A +8 more
europepmc +1 more source
Bioactive pigment production by marine bacteria from Colombian estuarine and deep-sea environments. [PDF]
Ríos-López LG +4 more
europepmc +1 more source
Nucleolar organization and divergent transcriptional machinery in Giardia lamblia: Structural insights and implications for drug targeting. [PDF]
Gaona-López C.
europepmc +1 more source

