Results 171 to 180 of about 26,423 (304)

Impacts of structural properties of myosin II filaments on force generation. [PDF]

Elife
Ding S, Chou PE, Deguchi S, Kim T.
europepmc   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Polymerization and stability of actin conjugated with polyethylene glycol. [PDF]

Biophys Physicobiol
Sagara M, Hatori K.
europepmc   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

The divergent intron-containing actin in sponge morphogenetic processes. [PDF]

NAR Genom Bioinform
Lyupina YV, Adameyko KI, Zubarev VM, Cherkasov AV, Ryabova AV, Mikhailov KV, Golyshev SA, Burakov AV, Finoshin AD, Erokhov PA, Sabirov MS, Zhurakovskaya AI, Ziganshin RH, Gornostaev NG, Ignatyuk VM, Kulikov AM, Mikhailov VS, Gazizova GR, Shagimardanova EI, Gusev OA, Khrameeva EE, Kravchuk OI.   +21 more
europepmc   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

アクチン配列情報解析 : I. アミノ酸配列アラインメント解析

, 1990
The amino acid sequence alignment analysis for 47 actins from various species was performed with AASEQ, a computer program system developed by us for a sequence information analysis study.
Shimizu, Toshio, Tanaka, Shuzo, Asai, Masatoshi   +2 more
core  

Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology. [PDF]

Mol Biol Cell
Velle KB, Onishi M.
europepmc   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Cardiac expressions of α- and β-myosin heavy chains and sarcomeric α- actins are regulated through transcriptional mechanisms. Results from nuclear run-on assays in isolated rat cardiac nuclei

, 1992
In the heart, mRNA accumulations for sarcomeric actins and myosin heavy chains (MHC) are subject to diverse regulatorial processes. To study cardiac contractile protein transcriptional regulations, an in vitro transcription system using nonenzymatically ...
Martin, X, Schwartz, K, Chassagne, C, Wisnewsky, C, Boheler, KR   +4 more
core