Actin at cell-cell junctions is composed of two dynamic and functional populations [PDF]
, 2005 Juankun Zhang +6 more
openalex +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Stabilization of adhesions controls F-actin architecture in mechanotransduction. [PDF]
Commun MaterCarney KR +6 more
europepmc +1 more source
Arabidopsis group Ie formins localize to specific cell membrane domains, interact with actin‐binding proteins and cause defects in cell expansion upon aberrant expression [PDF]
, 2005 Michael J. Deeks +7 more
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β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
The mechanism of dynamic steady states in lamellipodia. [PDF]
PLoS Comput BiolKim JH, Kim T.
europepmc +1 more source
Analysis of tarantula skeletal muscle protein sequences and identification of transcriptional isoforms [PDF]
, 2009 Jingui Zhu +5 more
core +1 more source
Actin Nucleation: Spire — Actin Nucleator in a Class of Its Own [PDF]
, 2005 Buzz Baum, Patricia Kunda
openalex +1 more source