Results 61 to 70 of about 982,671 (310)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

An Analysis of Action Competence Among Biology Education Students in the Context of Education for Sustainable Development

open access: yesBioeduca
Within the framework of developing Action Competence (AC) in Education for Sustainable Development (ESD), semester level is an important variable as it reflects students’ learning experiences, engagement, and academic maturity, as well as its ...
Sri Reski Ningsih, Dharma Ferry
doaj   +1 more source

PENGEMBANGAN MODEL PEMBINAAN KOMPETENSI CALON GURU MATEMATIKA MELALUI LESSON STUDY

open access: yesAksioma: Jurnal Program Studi Pendidikan Matematika, 2014
Education has a very important role in improving the quality of human resources. Therefore, education is expected to be one of the ways to prepare generations of qualified human resources and has the ability to deal with the progress of time and ...
Rahmad Bustanul Anwar, Dwi Rahmawati
doaj   +1 more source

Volitron: On a Psychodynamic Robot and Its Four Realities [PDF]

open access: yes, 2002
This paper discusses the concept of Volitron - a controller to make its host robot increase its competence in such activities as self-initiated exploration of an environment, new goal acquisition, and planning/executing of actions while taking into ...
Buller, Andrzej
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Seeding Knowledge Solutions Before, During, and After [PDF]

open access: yes, 2010
{Excerpt} In the age of competence, one must learn before, during, and after the event. Knowledge solutions lie in the areas of strategy development, management techniques, collaboration mechanisms, knowledge sharing and learning, and knowledge capture ...
Serrat, Olivier
core   +1 more source

Ambiguities and paradoxes in a competence-based approach to vocational education and training in France [PDF]

open access: yes, 2013
This article aims to show the effects of the prevalence of the competence regime within several sectors of vocational education and training in France.
Hébrard, Pierre
core   +2 more sources

Cultural competency: professional action and South Asian carers [PDF]

open access: yesJournal of Management in Medicine, 2002
Inequality and exclusion are characteristic of the experience of UK South Asian communities. In health care, community needs are often not addressed by health and social welfare services. An increase in cultural competency is now part of identified policy.
Mir, G., Tovey, P.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Implementation Of Clinical Supervision As An Effort To Improve Teacher's Pedagogic Competence In Implementing Learning In SD Nogosari UPT PPK Imogiri Bantul

open access: yesIdeguru, 2019
Teachers are professional educators. To carry out their duties in educating students, teachers must have sufficient competence. Teachers who have good competence are certainly also better able to carry out learning well, especially in pedagogical ...
Hariyono Hariyono
doaj   +1 more source

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