Results 51 to 60 of about 92,182 (313)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Penerapan Model Pembelajaran Relating, Experiencing, Applying, Cooperating, Transferring (REACT) untuk Meningkatkan Pemahaman Konsep Fisika SMA

Physics Education Research Journal, 2020
The aims of this study was to test the effectiveness of the Relating, Experiencing, Applying, Cooperating, Transferring (REACT) learning model in improving students' understanding of physics concepts.
Iqbal Sugita, Y R Liana, A F Lestari, Ani Rusilowati, Bambang Subali   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Using representational gesture to enact instants in collaborative problem solving in physics

Physical Review Physics Education Research
Embodied forms of representation like gesture have been shown to play an important role in how learners conceptualize phenomena in physics; however, we know little about how students use gesture to capture the idea of instantaneity. Drawing on multimodal
Emma Teresa Booth, Virginia J. Flood, Benedikt W. Harrer   +2 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Lie Group Statistics and Lie Group Machine Learning Based on Souriau Lie Groups Thermodynamics & Koszul-Souriau-Fisher Metric: New Entropy Definition as Generalized Casimir Invariant Function in Coadjoint Representation

Entropy, 2020
In 1969, Jean-Marie Souriau introduced a “Lie Groups Thermodynamics” in Statistical Mechanics in the framework of Geometric Mechanics. This Souriau’s model considers the statistical mechanics of dynamic systems in their “space of evolution” associated to
Frédéric Barbaresco
doaj   +1 more source

Collaborative physics teachers: Enhancing the use of the laboratory through action research in a community of learners [PDF]

, 2023
Marta Carli, Ornella Pantano
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Penanaman Karakter Positif Pelajar Melalui Pembahasan Fenomena-Fenomena Fisika dan Pendekatan Analogi (Hasil Kajian Perkulihan Fisika Dasar)

JPFT (Jurnal Pendidikan Fisika dan Teknologi), 2017
The discussion results of Fundamental Physics I lecturing, especially the 1st Newton law about movement, law of Lenz, electromagnetic induction, and law of Bernoulli about pressure of flowing fluid show that in the concepts implicitly there is an action ...
Joni Rokhmat
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source