PO-02-150 SPATIAL HETEROGENEITY OF ACTION POTENTIAL DURATION IN THE INTACT RABBIT VENTRICLE UNDER LONG QT CONDITIONS [PDF]
, 2023 Rebecca J. Gilchrist +3 more
openalex +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Interpretable machine learning of action potential duration restitution kinetics in single-cell models of atrial cardiomyocytes [PDF]
, 2022 Jun-Seop Song, Young-Seon Lee
openalex +3 more sources
, 2015 This paper demonstrates synergetic influences of systems thinking upon a third cycle of action research aimed at improve teaching skills and the student experience.
Cameron, Leone Carol
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Phenanthrene impacts zebrafish cardiomyocyte excitability by inhibiting IKr and shortening action potential duration. [PDF]
J Gen Physiol, 2021 Kompella SN +3 more
europepmc +1 more source
Gaming simulations with Action Learning for community-based disaster reduction training
, 2016 n this paper, I introduced how Action Learning is adaptable with Gaming Simulation to the context of community-based disaster reduction. With containing the characteristics of Action Learning, I showed theoretically that Gaming Simulation can be an ...
Toyoda, Yusuke
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2015 This article provides a creative analysis of reflective thought processes grounded in the systemic thinking of an autobiographical account of action-research journeys from the context of action-learning experiences that led to the discovery of the ...
Tetteh, Emmanuel Nii Ayikwei
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source