Results 161 to 170 of about 12,692,953 (333)
Role of beta-adrenergic modulation of action potential duration in arrhythmogenesis in Long QT Syndrome Type 1 & 2 [PDF]
Zhia Lim +7 more
openalex +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Pharmacological activation of exchange protein directly activated by cAMP 1 (EPAC1) increases action potential duration in mouse atrial myocytes [PDF]
, 2022 Arthur Boilève +5 more
openalex +1 more source
Reflections for postgraduate students on writing an action research thesis
, 2017 The prospect of conducting action research as part of formal academic study can seem quite daunting for many. The academy, often dominated by a positivist approach, does not always appreciate the value and quality of research that is qualitative, action ...
Smith, Steve Wayne
core
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Thrombospondin-4 induces prolongation of action potential duration in rat isolated ventricular myocytes. [PDF]
J Vet Med Sci, 2020 Imoto K +4 more
europepmc +1 more source
How Changes in Unemployment Benefit Duration Affect the Inflow Into Unemployment [PDF]
We study how changes in the maximum benefit duration affec the inow into unemployment in the Netherlands. Until August 2003, workers who became un- employed after age 57.5 were entitled to unemployment benefits until the age of 65, after which they would
Tuit, S., Ours, J.C. van
core +2 more sources
An action learning intervention on work-family balance
, 2020 The purpose of this paper is to explore the impact of an action learning intervention using positive psychological techniques to impact work-family balance. It draws on theory and practice from positive psychology and action learning interventions.
Carr, Rodney +2 more
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source