Results 101 to 110 of about 515,184 (299)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Water quality assessment, trophic classification and water resources management

open access: yes, 2010
Quantification of water quality (WQ) is an integral part of scientifically based water resources management. The main objective of this study was comparative analysis of two approaches applied for quantitative assessment of WQ: the trophic level index ...
Gal, Gideon   +4 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An Action Research Intervention Towards Overcoming “Theory Resistance” in Photojournalism Students [PDF]

open access: yes, 2015
Account of an action research project designed to understand and overcome 'theory resistance' in undergraduate photojournalism students, based on the Academic Literacies model.
Good, Jennifer, Jennifer Good
core   +1 more source

Multi-Stage Contrastive Regression for Action Quality Assessment

open access: yesICASSP 2024 - 2024 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)
In recent years, there has been growing interest in the video-based action quality assessment (AQA). Most existing methods typically solve AQA problem by considering the entire video yet overlooking the inherent stage-level characteristics of actions. To address this issue, we design a novel Multi-stage Contrastive Regression (MCoRe) framework for the ...
Qi An, Mengshi Qi, Huadong Ma
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Enhancing continuing nursing education: a participatory action research approach in Iran

open access: yesBMC Medical Education
Background Continuing nursing education is a crucial tool for advancing the nursing profession. Numerous studies have highlighted the suboptimal quality of continuing education programs.
Hojat Mohsen, Karimyar Jahromi Mahdi
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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