Results 121 to 130 of about 2,560,141 (301)

Many Strong Voices: Outline for an assessment project design [PDF]

open access: yes, 2008
This document defines, guides, and supports the development and implementation of a full assessment of vulnerability and adaptation to climate change in Small Island Developing States (SIDS), under the Many Strong Voices (MSV) programme.
CICERO, Senter for klimaforskning   +1 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Analysis Of The Quality Improvement Management Process Through PDSA At Puskesmas Sidoarjo Sidoarjo District

open access: yesMedical Technology and Public Health Journal
Improving the quality of health center is very important to realize quality and equitable health services. This study aims to analyze the implementation of continuous quality management through the PDSA (Plan-Do-Study-Action) cycle at Sidoarjo Health ...
Frysca Virnanda Retikasari   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Health, biodiversity, and natural resource use on the Amazon frontier: an ecosystem approach

open access: yesCadernos de Saúde Pública, 2001
This study aims to improve the health of rural Amazonian communities through the development and application of a participatory ecosystem approach to human health assessment. In the study area marked seasonal fluctuations dictate food availability, water
Murray Tamsyn P., Sánchez-Choy José
doaj  

A Single Conjunction Risk Assessment Metric: the F-Value [PDF]

open access: yes, 2009
The Conjunction Assessment Team at NASA Goddard Space Flight Center provides conjunction risk assessment for many NASA robotic missions. These risk assessments are based on several figures of merit, such as miss distance, probability of collision, and ...
Frigm, Ryan Clayton, Newman, Lauri K.
core   +1 more source

Informal assessment for library middle managers

open access: yes, 2010
Library middle managers juggle a variety of responsibilities. They are responsible for supervisory tasks such as coaching and team building. They are responsible for the service their unit provides or the output of their unit.
Brown, Jeanne M
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Home - About - Disclaimer - Privacy