Results 131 to 140 of about 515,184 (299)

Health, biodiversity, and natural resource use on the Amazon frontier: an ecosystem approach

open access: yesCadernos de Saúde Pública, 2001
This study aims to improve the health of rural Amazonian communities through the development and application of a participatory ecosystem approach to human health assessment. In the study area marked seasonal fluctuations dictate food availability, water
Murray Tamsyn P., Sánchez-Choy José
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Formative feedback to improve learning on a teacher education degree using a personal learning environment

open access: yes, 2007
This paper reports on an action research project involving a structured, formative assessment feedback process, within a personal learning environment (PLE), to address concerns about effectiveness of previous course delivery.
Ross, Magnus   +3 more
core  

How can I use Irish language e-portfolios in the assessment for learning approach in my primary classroom? [PDF]

open access: yes, 2009
This paper investigates the process of assessment for learning (AfL) in the primary school Irish language classroom. Electronic portfolios (e-portfolios) are used as a tool in assessment for learning with eight of my second class pupils in an urban ...
Clerkin, Martina
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluating the effectiveness and limitations of online health information tools in assessing the quality of medication-related content

open access: yesFrontiers in Public Health
IntroductionThe internet has become a primary source of information on medicines, yet the quality of this information is inconsistent. Despite the proliferation of web-based resources, limited research has specifically examined the reliability of online ...
Adel S. Alhlayl, Haitham A. Alzghaibi
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Quality assessment methodology and tools

open access: yes, 2012
The paper introduced the work done by Working Group 3 in the field of the research COST TU0701 "Improving the Quality of Suburban Building Stock". The main aim of Task 6 of the Action “Quality assessment models and protocols” developed by Working Group 3
BRUNORO, Silvia, Wetzel C.
core  

PERBAIKAN KUALITAS PEMBELAJARAN KEWIRAUSAHAAN DENGAN MENERAPKAN STRATEGI OPTIMALISASI KEPEMIMPINAN GURU MELALUI LEARNING MANAGER PADA SISWA KELAS X TATA BUSANA 2 DI SMK NEGERI 3 PATI

open access: yesJurnal Pendidikan Ilmu Sosial, 2015
This study aims to determine to describe: (1) implement measures to optimize learning strategies teacher leadership through learning manager as efforts to improve the quality of teaching Entrepreneurship in students of Class X Fashion 2 di SMK Negeri 3 ...
Sri Puji Haryati
doaj  

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