Results 141 to 150 of about 14,186,648 (294)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 2009 In October 2009, the National Quality Council through the NQC Quality of Assessment Action Group appointed a consortium, comprising Victoria University of Technology, Bateman and Giles Pty Ltd and Learning Australia Pty Ltd, to design and implement a ...
Stowell, Rob +3 more
core
DiagnosticsDigital pathology continues to gain momentum, with the promise of artificial intelligence to aid diagnosis and for assessment of features which may impact prognosis and clinical management.
Lisa Browning +11 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Respiratory syncytial virus (RSV) is a virus that infects the lungs and upper airways. This virus spreads every winter, with the RSV season in Ireland typically running from October to March.
Health Information and Quality Authority (HIQA)
core
, 2022 At the request of the Department of Health, HIQA undertook a descriptive analysis of epidemiological indicators in order to describe the burden of COVID-19 as it has occurred across a range of European countries from 1 January 2020 up to 30 November ...
Health Information and Quality Authority (HIQA)
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
PECoP: Parameter Efficient Continual Pretraining for Action Quality Assessment
2024 IEEE/CVF Winter Conference on Applications of Computer Vision (WACV)The limited availability of labelled data in Action Quality Assessment (AQA), has forced previous works to fine-tune their models pretrained on large-scale domain-general datasets. This common approach results in weak generalisation, particularly when there is a significant domain shift.
Amirhossein Dadashzadeh +3 more
openaire +2 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Health, biodiversity, and natural resource use on the Amazon frontier: an ecosystem approach
Cadernos de Saúde Pública, 2001 This study aims to improve the health of rural Amazonian communities through the development and application of a participatory ecosystem approach to human health assessment. In the study area marked seasonal fluctuations dictate food availability, water
Murray Tamsyn P., Sánchez-Choy José
doaj